Author
Cameron Willden
Bio: Cameron Willden is an academic researcher. The author has an hindex of 1, co-authored 2 publications receiving 33 citations.
Papers
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TL;DR: Mixexp as discussed by the authors provides functions for creating mixture designs composed of extreme vertices and edge and face centroids in constrained mixture regions where components are subject to upper, lower and linear constraints.
Abstract: This article discusses the design and analysis of mixture experiments with R and illustrates the use of the recent package mixexp. This package provides functions for creating mixture designs composed of extreme vertices and edge and face centroids in constrained mixture regions where components are subject to upper, lower and linear constraints. These designs cannot be created by other R packages. mixexp also provides functions for graphical display of models fit to data from mixture experiments that cannot be created with other R packages.
46 citations
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TL;DR: Interestingly, the smallest PDIs were obtained at 30°C, and the cosurfactant concentration was able to be adjusted to optimize the formulation and to obtain nanoemulsions in the 20-120nm range with a PDI smaller than 0.14.
47 citations
TL;DR: It is identified that an optimum dietary macronutrient balance of a low protein, medium carbohydrate and fat diet can ameliorate key PCOS reproductive traits, but PCOS mice display a hindered ability for their metabolic system to respond to diet variations, and varying macronUTrient balance did not have a beneficial effect on the development of metabolic PCOS traits.
Abstract: Lifestyle, mainly dietary, interventions are first-line treatment for women with polycystic ovary syndrome (PCOS), but the optimal diet remains undefined. We combined a hyperandrogenized PCOS mouse model with a systematic macronutrient approach, to elucidate the impact of dietary macronutrients on the development of PCOS. We identify that an optimum dietary macronutrient balance of a low protein, medium carbohydrate and fat diet can ameliorate key PCOS reproductive traits. However, PCOS mice display a hindered ability for their metabolic system to respond to diet variations, and varying macronutrient balance did not have a beneficial effect on the development of metabolic PCOS traits. We reveal that PCOS traits in a hyperandrogenic PCOS mouse model are ameliorated selectively by diet, with reproductive traits displaying greater sensitivity than metabolic traits to dietary macronutrient balance. Hence, providing evidence to support the development of evidence-based dietary interventions as a promising strategy for the treatment of PCOS, especially reproductive traits. Lifestyle interventions are first-line treatment for women with polycystic ovary syndrome (PCOS), but the optimal diet remains undefined. Here the authors identify an optimum dietary macronutrient balance that can rectify PCOS reproductive traits in a mouse model of PCOS, while metabolic features were less sensitive to diet changes.
41 citations
TL;DR: This modern statistics for engineering and quality improvement is well known book in the world, of course many people will try to own it and this is it the book that you can receive directly after purchasing.
Abstract: Why should wait for some days to get or receive the modern statistics for engineering and quality improvement book that you order? Why should you take it if you can get the faster one? You can find the same book that you order right here. This is it the book that you can receive directly after purchasing. This modern statistics for engineering and quality improvement is well known book in the world, of course many people will try to own it. Why don't you become the first? Still confused with the way?
33 citations
TL;DR: Self- nanoemulsifying drug delivery system SNEDDS is a promising carrier for voriconazole ocular delivery and exhibited a significant improvement in apparent permeability coefficient when compared to commercialized formulation.
Abstract: The aim of this study was to develop self- nanoemulsifying drug delivery system (SNEDDS) to improve the transcorneal permeability of voriconazole. A ‘mixture design around a reference mixture’ appr...
23 citations
TL;DR: In this article, the International Platform of Biodiversity and Ecosystem Services (IPBES) recommends pluralistic valuations of ecosystem services that include intrinsic, instrumental, and relational values to understand how value pluralism may affect trade-offs between ecosystem services.
Abstract: Trade-offs between incommensurable values of services are a challenge to the implementation of the ecosystem services framework The International Platform of Biodiversity and Ecosystem Services (IPBES) recommends pluralistic valuations of ecosystem services that include intrinsic, instrumental, and relational values To understand how value pluralism may affect trade-offs between ecosystem services, we conducted a study quantifying ecosystem service proxies along a tree species diversity gradient in plantation forests in the coastal Pacific Northwest, USA Further, we developed four frameworks emphasizing different bundles of ecosystem services based on how the services clumped within a matrix of value types and level of social organization at which benefits are likely to accrue We then determined tree species compositions that optimized ecosystem services emphasized under the four frameworks Some ecosystem services responded in sync, but we found trade-offs between provisioning services with primarily instrumental value and cultural services with relational values Most single ecosystem services were maximized by monocultures In contrast, high levels of tree species diversity supported the largest variety of value types We hypothesized that biodiversity may be important not just for increasing ecosystem functions and services, but also for value pluralism
21 citations