Carla G. van El

TL;DR: Focusing on the clinical diagnostics setting, this paper is intended to contribute to the discussion and the development of guidelines in this fast-moving field, and provide recommendations for health-care professionals.

TL;DR: This document argues for a cautious expansion of the scope of prenatal screening to serious congenital and childhood disorders, only following sound validation studies and a comprehensive evaluation of all relevant aspects.

TL;DR: The challenges that expanded carrier screening might pose in the context of the lessons learnt from decades of population-based carrier screening and in thecontext of existing screening criteria are discussed.

TL;DR: Expectations of benefits and potential use of genetic testing have been raised among the public, resulting in more positive opinions, and worries on inequity remain, although worries about premium differentiation by insurance companies have decreased.

TL;DR: Genetic testing and common disorders in a public health framework: how to assess relevance and possibilities as mentioned in this paper, where the authors assess relevance, possibilities, relevance, and relevance of common disorders.