C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
Papers
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Journal ArticleDOI
microRNAs as Anti-Cancer Therapy
TL;DR: This review provides a comprehensive overview of miRNAs with established functional relevance in cancer and approaches towards therapeutic miRNA-based intervention are discussed, including viral or non-viral approaches of miRNA replacement therapy in the case of tumor-suppressing miRNAAs and strategies for the inhibition of oncogenic miRNas.
Journal Article
Characterization and localization of the TCL-1 oncogene product.
Tie-bo Fu,Laura Virgilio,Maria Grazia Narducci,Antonio Facchiano,Giandomenico Russo,Carlo M. Croce +5 more
TL;DR: The TCL-1 protein has considerable sequence similarities to the product of the MTCP-1 gene on chromosome Xq28, which is involved in T cell lympho-proliferative diseases, and may represent a member of a novel family of genes involved in lymphoid proliferation and/or survival and in Tcell malignancies.
Journal ArticleDOI
Knockout mice reveal a tumor suppressor function for Testin
Alessandra Drusco,Nicola Zanesi,Claudia Roldo,Francesco Trapasso,John L. Farber,Louise Y.Y. Fong,Carlo M. Croce +6 more
TL;DR: Data suggest that Tes functions as a tumor suppressor gene in vivo, and generates a Tes knockout mouse and uses it in an established model of carcinogen-induced gastric cancer.
Patent
Microrna signatures associated with human chronic lymphocytic leukemia (ccl) and uses thereof
Carlo M. Croce,George A. Calin +1 more
TL;DR: In this paper, methods and compositions for the diagnosis, prognosis and/or treatment of leukemia associated diseases are disclosed. But, they do not discuss the treatment of these diseases.
Journal ArticleDOI
FHIT Suppresses Epithelial-Mesenchymal Transition (EMT) and Metastasis in Lung Cancer through Modulation of MicroRNAs
Sung Suk Suh,Ji Young Yoo,Ri Cui,Balveen Kaur,Kay Huebner,Taek-Kyun Lee,Rami I. Aqeilan,Carlo M. Croce +7 more
TL;DR: It is demonstrated that the expression pattern of FHIT and miR-30c is inversely correlated with that of MTDH and HMGA2 in normal tissue, non-metastatic and metastatic tumors, serving as a potential biomarker for metastasis in lung cancer.