C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
Antiapoptosis potential of bcl-2 oncogene by dephosphorylation.
TL;DR: Investigation indicates that the phosphorylation pathway involving bcl-2 can be the determinant of cell death in lymphocytes, and phosphoamino acid analysis reveals that bCl-2 is phosphorylated at a serine residue.
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A Differential MicroRNA Profile Distinguishes Cholangiocarcinoma from Pancreatic Adenocarcinoma
Amy L. Collins,Sylwia E. Wojcik,James Liu,Wendy L. Frankel,Hansjuerg Alder,Lianbo Yu,Thomas D. Schmittgen,Carlo M. Croce,Mark Bloomston +8 more
TL;DR: Cholangiocarcinoma has a distinct miR profile from pancreatic adenocarc inoma, and discrimination between these two tumor types may be possible with as few as seven miRs.
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MicroRNAs 221 and 222 Inhibit Normal Erythropoiesis and Erythroleukemic Cell Growth Via Kit Receptor Downmodulation.
Nadia Felli,Laura Fontana,Elvira Pelosi,Rosanna Botta,Désirée Bonci,Francesco Facchiano,Francesca Liuzzi,Valentina Lulli,Ornella Morsilli,Simona Santoro,Mauro Valtieri,Mauro Valtieri,Chang Gong Liu,Antonio Sorrentino,Antonio Sorrentino,Carlo M. Croce,Cesare Peschle,Cesare Peschle +17 more
TL;DR: In human erythropoiesis the decline of miR 221 and 222 unblocks Kit protein production at translational level, thus leading to expansion of early E cells, suggesting a potential role of these microRNAs in cancer therapy.
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Zinc Replenishment Reverses Overexpression of the Proinflammatory Mediator S100A8 and Esophageal Preneoplasia in the Rat
Cristian Taccioli,Shaogui Wan,Chang Gong Liu,Hansjuerg Alder,Stefano Volinia,John L. Farber,Carlo M. Croce,Louise Y.Y. Fong,Louise Y.Y. Fong +8 more
TL;DR: The finding that zinc regulates an inflammatory pathway in esophageal carcinogenesis may lead to prevention and therapy for this cancer and modulates the link between S100A8-RAGE interaction and downstream nuclear factor kappaBeta/COX-2 signaling.
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Chimeric mice derived from human-mouse hybrid cells.
TL;DR: The results demonstrate that, after in vitro culture and selection, at least some of the human-mouse hybrid cells still retain their in vivo potential to differentiate and become functionally integrated in the living organism.