C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
Papers
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Journal ArticleDOI
Transcribed ultraconserved noncoding RNAs (T-UCR) are involved in Barrett's esophagus carcinogenesis
Matteo Fassan,Luigi Dall'Olmo,Marco Galasso,Chiara Braconi,Marco Pizzi,Stefano Realdon,Stefano Volinia,Nicola Valeri,Pierluigi Gasparini,Raffaele Baffa,Rhonda F. Souza,Caterina Vicentini,Edoardo D'Angelo,Jan Bornschein,Gerard J. Nuovo,Giovanni Zaninotto,Carlo M. Croce,Massimo Rugge +17 more
TL;DR: This study is the first demonstration of a role for T-UCRs in the transformation of Barrett's mucosa, and analogous BE-specific T- UCR profiles were shared by human and murine lesions.
Journal ArticleDOI
Virus-encoded microRNA contributes to the molecular profile of EBV-positive Burkitt lymphomas
Pier Paolo Piccaluga,Mohsen Navari,Mohsen Navari,Giulia De Falco,Giulia De Falco,Maria Raffaella Ambrosio,Stefano Lazzi,Fabio Fuligni,Cristiana Bellan,Maura Rossi,Maria Rosaria Sapienza,Maria Antonella Laginestra,Maryam Etebari,Emily A Rogena,Lynnette K Tumwine,Claudio Tripodo,Davide Gibellini,Jessica Consiglio,Carlo M. Croce,Stefano Pileri,Lorenzo Leoncini +20 more
TL;DR: Investigation of the molecular profiles of Epstein-Barr virus-positive and -negative BL found significant differences in the expression of viral microRNAs and in selected target genes, and provided solid evidences that the EBV-encoded micro RNAs significantly mold the transcriptional landscape of Burkitt Lymphoma clones.
Journal ArticleDOI
TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia
Antonella Bresin,Lucilla D'Abundo,Maria Grazia Narducci,Maria Teresa Fiorenza,Carlo M. Croce,Massimo Negrini,Giandomenico Russo +6 more
TL;DR: This is a review of the CLL biology arising from work of many independent investigators who have used TCL1 transgenic mouse model focusing on pathogenetic, microenviroment and therapeutic targets.
Journal ArticleDOI
Quaking and miR-155 interactions in inflammation and leukemogenesis
Esmerina Tili,Marcela Chiabai,Dario Palmieri,Melissa Brown,Ri Cui,Cecilia Fernandes,Tim Richmond,Taewan Kim,Tyler Sheetz,Hui Lung Sun,Alessandro Laganà,Dario Veneziano,Stefano Volinia,Laura Z. Rassenti,Thomas J. Kipps,Hamdy Awad,Jean Jacques Michaille,Jean Jacques Michaille,Carlo M. Croce +18 more
TL;DR: The expression of QKI is reduced in lipopolysaccharide (LPS)-challenged macrophages, suggesting that Qki is a key regulator of LPS signaling pathway, and data implicate QKI in the pathophysiology of inflammation and oncogenesis where miR-155 is involved.
Patent
Oncogenic ALL-1 Fusion Proteins for Targeting Drosha-Mediated MicroRNA Processing
TL;DR: In this paper, compositions and methods for reducing the proliferation of ALL cancer cells through targeted interactions with ALL1 fusion proteins are described and discussed. But none of the methods are suitable for the use of ALL fusion proteins in medical applications.