C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
The High Mobility Group A proteins contribute to thyroid cell transformation by regulating miR-603 and miR-10b expression.
TL;DR: Analysis of the miRNA expression profile of v‐ras‐Ki oncogene‐transformed thyroid cells expressing or not HMGA1 proteins shows that, among the miRNAs regulated by cell transformation, there are miR‐10b, miR•21, miB‐125b,miR‐125 b, mi R‐221 and miR •222 that are positively regulated byHMGA1 expression, andMiR‐34a and miG‐603 that are
Journal Article
Genetic approaches to the study of the molecular basis of human cancer.
TL;DR: A potential candidate involved in the 3p deletion characteristic of lung cancer has been identified and it will indicate that transmembrane protein tyrosine phosphatase may represent a class of tumor suppressors.
Book ChapterDOI
The role of deletions at the FRA3B/FHIT locus in carcinogenesis.
TL;DR: Analysis of the approximately 300-kb DNA sequence encompassing FHIT exon 5 in the FRA3B epicenter has provided clues to the mechanism of repair of the fragile site double strand breaks and suggests that the FHit gene is a tumor suppressor gene whose inactivation may drive clonal expansion of preneoplastic and neoplastic cells.
Journal ArticleDOI
miR-340 predicts glioblastoma survival and modulates key cancer hallmarks through down-regulation of NRAS.
Danilo Fiore,Elvira Donnarumma,Giuseppina Roscigno,Margherita Iaboni,Valentina Russo,Alessandra Affinito,Assunta Adamo,Fabio De Martino,Cristina Quintavalle,Giulia Romano,Adelaide Greco,Ylermi Soini,Arturo Brunetti,Carlo M. Croce,Gerolama Condorelli +14 more
TL;DR: It is demonstrated that expression of miR-340 in glioblastoma is responsible for a strong tumor-suppressive effect in LTS patients by down-regulating NRAS, and may be developed into a tool to improve treatment of gliOBlastoma.
Journal Article
Characterization of the Human Homologue of RAD54: A Gene Located on Chromosome 1p32 at a Region of High Loss of Heterozygosity in Breast Tumors
Debora Rasio,Yoshiki Murakumo,David J. Robbins,Timothy J. Roth,Aaron Silver,Massimo Negrini,Carl J. Schmidt,John D. Burczak,Richard Fishel,Carlo M. Croce +9 more
TL;DR: The complete cDNA sequence and the characterization of the genomic locus coding for the human homologue of the yeast RAD54 gene (hRAD54) are described and, although the gene region appears to be deleted in several tumors, at present no coding sequence mutations are found.