C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model
Nicola Zanesi,Veronica Balatti,Jesse D. Riordan,Aaron Burch,Lara Rizzotto,Alexey Palamarchuk,Luciano Cascione,Alessandro Laganà,Adam J. Dupuy,Carlo M. Croce,Yuri Pekarsky +10 more
TL;DR: Findings demonstrate cooperation of Tcl1 and the NF-kB pathway in the pathogenesis of aggressive CLL and will result in the development of combinatorial therapies to treat CLL.
Journal ArticleDOI
MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors
Matteo Rossi,David Colecchia,Gennaro Ilardi,Mario Acunzo,Giovanni Nigita,Federica Sasdelli,Angela Celetti,Angela Strambi,Stefania Staibano,Carlo M. Croce,Mario Chiariello +10 more
TL;DR: The findings suggest that MAPK15 overexpression may contribute to the malignant transformation of germ cells by controlling a “stress support” autophagic pathway, able to prevent DNA damage and the consequent activation of the p53 tumor suppressor.
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Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia
Angelo Veronese,Felice Pepe,J Chiacchia,Sara Pagotto,Paola Lanuti,Serena Veschi,M Di Marco,Andrea D’Argenio,Idanna Innocenti,Barbara Vannata,Francesco Autore,Marco Marchisio,Dorothee Wernicke,Fabio Verginelli,Giuseppe Leone,Laura Z. Rassenti,Thomas J. Kipps,Renato Mariani-Costantini,Luca Laurenti,Carlo M. Croce,Rosa Visone +20 more
TL;DR: In a subset of CLL patients harboring 13q14 deletions, exclusive RNA polymerase III (RPIII)-driven transcription of the miR-15a/16-1 was the consequence of loss of the RPII-regulated allele and correlated with high expression of the poor prognostic marker ZAP70 (P=0.019).
Journal ArticleDOI
Assignment of gene(s) for cell transformation to human chromosome 7 carrying the simian virus 40 genome.
Carlo M. Croce,Hilary Koprowski +1 more
TL;DR: Since the expression of the transformed phenotype was always associated with the presence of the human chromosome 7, which carries the SV40 genome, it is concluded that this chromosome contains gene(s) coding for "transforming factor(s)."