C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal Article
Partial Tandem Duplication of ALL1 as a Recurrent Molecular Defect in Acute Myeloid Leukemia with Trisomy 11
Michael A. Caligiuri,Matthew P. Strout,Steven A. Schichman,Krzysztof Mrózek,Diane C. Arthur,Geoffrey P. Herzig,Maria R. Baer,Charles A. Schiffer,Kristiina Heinonen,Sakari Knuutila,Tapio Nousiainen,Tapani Ruutu,AnneMarie W. Block,Philip Schulman,Jens Pedersen-Bjergaard,Carlo M. Croce,Clara D. Bloomfield +16 more
TL;DR: The finding of the ALL1 duplication as a consistent defect in patients with +11 represents the first identification of a specific gene rearrangement associated with recurrent trisomy in human cancer.
Journal Article
Cell Permeable Bcl-2 Binding Peptides: A Chemical Approach to Apoptosis Induction in Tumor Cells
Jia-Lun Wang,ZhiJia Zhang,Swati Choksi,Simei Shan,Zhixian Lu,Carlo M. Croce,Emad S. Alnemri,Robert Korngold,Ziwei Huang +8 more
TL;DR: A cell permeable Bcl-2 binding peptide, cpm-1285, was designed by chemically attaching a fatty acid to a peptide derived from the proapoptotic protein Bad and had in vivo activity in slowing human myeloid leukemia growth in severe combined immunodeficient mice.
Journal Article
Rarity of Somatic and Germline Mutations of the Cyclin-dependent Kinase 4 Inhibitor Gene, CDK4I, in Melanoma
Masataka Ohta,Hirokazu Nagai,Masayoshi Shimizu,Debora Rasio,David Berd,Michael J. Mastrangelo,Arun D. Singh,Jerry A. Shields,Carol L. Shields,Carlo M. Croce,Kay Huebner +10 more
TL;DR: In this article, the inhibitor of cyclin-dependent kinase 4 (CDK4I ; also known as 16p INK4, multiple tumor suppressor 1, or CDKN2 gene) has been mapped to 9p21 and shown to be mutated or deleted in a large fraction of cell lines derived from many tumor types, including melanoma.
Journal Article
Association between Cigarette Smoking and FHIT Gene Alterations in Lung Cancer
Gabriella Sozzi,Laura Sard,L. De Gregorio,Antonio Marchetti,Katia Musso,Fiamma Buttitta,Silvana Tornielli,Silvia Pellegrini,Maria Luisa Veronese,Giacomo Manenti,Matteo Incarbone,Antonio Chella,Carlo Alberto Angeletti,Ugo Pastorino,Kay Huebner,G. Bevilaqua,S. Pilotti,Carlo M. Croce,M. A. Pierotti +18 more
TL;DR: A molecular analysis of microsatellite alterations within the FHIT gene and FRA3B and at an independent locus on chromosome 10, D10S197, in lung tumors from heavy smokers and in tumors from never smokers suggests that FH IT is a candidate molecular target of carcinogens contained in tobacco smoke.
Journal ArticleDOI
MicroRNAs in the Pathogenesis of Cancer
TL;DR: The findings reveal a potential and appealing role for miRs as cancer therapeutic targets and aims at providing the molecular bases for the understanding of the potential role of miRs in the translational and clinical setting.