C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
Targeting microRNAs in cancer: rationale, strategies and challenges.
TL;DR: The role of miRNAAs in tumorigenesis is described and the rationale, the strategies and the challenges for the therapeutic targeting of miRNAs in cancer are critically discussed.
Journal ArticleDOI
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
George A. Calin,Chang Gong Liu,Cinzia Sevignani,Manuela Ferracin,Nadia Felli,Nadia Felli,Calin Dan Dumitru,Masayoshi Shimizu,Amelia Cimmino,Simona Zupo,Marielia Dono,Marie Dell'Aquila,Hansjuerg Alder,Laura Z. Rassenti,Thomas J. Kipps,Florencia Bullrich,Florencia Bullrich,Massimo Negrini,Carlo M. Croce,Carlo M. Croce +19 more
TL;DR: Genomewide expression profiling of miRNAs in human B cell chronic lymphocytic leukemia (CLL) is reported by using a microarray containing hundreds of human precursor and mature miRNA oligonucleotide probes, suggesting that miRNA expression patterns have relevance to the biological and clinical behavior of this leukemia.
PatentDOI
MicroRNA Signatures in Human Ovarian Cancer
TL;DR: In this paper, the authors presented novel methods for the diagnosis of ovarian cancer using at least one miR selected from miR-200b, miR -200b and miR −200c.
Journal ArticleDOI
miRNAs, cancer, and stem cell division.
Carlo M. Croce,George A. Calin +1 more
TL;DR: As a cluster of recent Nature papers now show, altered expression of specific miRNA genes contributes to the initiation and progression of cancer.
Journal ArticleDOI
Modulation of miR-155 and miR-125b Levels following Lipopolysaccharide/TNF-α Stimulation and Their Possible Roles in Regulating the Response to Endotoxin Shock
Esmerina Tili,Jean-Jacques Michaille,Jean-Jacques Michaille,Amelia Cimino,Stefan Costinean,Calin Dan Dumitru,Brett Adair,Muller Fabbri,Hannes Alder,Chang Gong Liu,George A. Calin,Carlo M. Croce +11 more
TL;DR: The data suggest that the LPS/TNF-α-dependent regulation of miR-155 and miR -125b may be implicated in the response to endotoxin shock, thus offering new targets for drug design.