C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2
TL;DR: It is demonstrated that the binding of KL to its tyrosine kinase receptor results in the upregulation of bcl-2, thereby preventing apoptosis in this subset of normal human lymphocytes, and this survival mechanism may be operative for CD56bright NK cells in vivo.
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Physical and Functional Interactions between the Wwox Tumor Suppressor Protein and the AP-2γ Transcription Factor
Rami I. Aqeilan,Alexey Palamarchuk,Ronald J. Weigel,Juan J. Herrero,Yuri Pekarsky,Carlo M. Croce +5 more
TL;DR: The results suggest that Wwox tumor suppressor protein inhibits AP-2γ oncogenic activity by sequestering it in the cytoplasm and suppressing its transactivating function.
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Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer
Claudia Piovan,Dario Palmieri,Gianpiero Di Leva,Luca Braccioli,Patrizia Casalini,Gerard J. Nuovo,Monica Tortoreto,Marianna Sasso,Ilaria Plantamura,Tiziana Triulzi,Cristian Taccioli,Cristian Taccioli,Elda Tagliabue,Marilena V. Iorio,Carlo M. Croce +14 more
TL;DR: It is shown that miR‐205, on cosuppressive microRNA lost in breast cancer, is directly transactivated by oncosuppressor p53.
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Role of miR-15/16 in CLL
Yuri Pekarsky,Carlo M. Croce +1 more
TL;DR: The discovery, functions, clinical relevance and treatment opportunities related to miR-15/16 are discussed, as this microRNA cluster targets multiple oncogenes, including BCL2, Cyclin D1, MCL1 and others.
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Production of antibodies against influenza virus by somatic cell hybrids between mouse myeloma and primed spleen cells
TL;DR: The somatic cell hybrids between mouse myeloma cells and spleen cells derived from a BALB/c mouse immunized with purified influenza virus found to produce large amounts of antibodies specific for the hemagglutinin of the virus.