C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
Deregulated expression of TCL1 causes T cell leukemia in mice.
Laura Virgilio,Cristina Lazzeri,Roberta Bichi,Ken-ichi Nibu,Maria Grazia Narducci,Giandomenico Russo,Jay L. Rothstein,Carlo M. Croce +7 more
TL;DR: It is demonstrated that transcriptional activation of the TCL1 protooncogene can cause malignant transformation of T lymphocytes, indicating the role of TCL2 in the initiation of malignant transformed T cell neoplasia in T prolymphocytic leukemias and T chronic lymphocyticLeukmias.
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Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status.
Gianpiero Di Leva,Claudia Piovan,Pierluigi Gasparini,Apollinaire Ngankeu,Cristian Taccioli,Cristian Taccioli,Daniel Briskin,Douglas G. Cheung,Brad Bolon,Laura Anderlucci,Laura Anderlucci,Hansjuerg Alder,Gerard J. Nuovo,Meng Li,Marilena V. Iorio,Marco Galasso,Santhanam Ramasamy,Guido Marcucci,Danilo Perrotti,Kimerly A. Powell,Anna Bratasz,Michela Garofalo,Kenneth P. Nephew,Carlo M. Croce +23 more
TL;DR: It is demonstrated that the miR-191/425 cluster, by reducing the expression of an extensive network of genes, has a fundamental impact on cancer initiation and progression of breast cancer cells.
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At least ten genes define the imprinted Dlk1-Dio3 cluster on mouse chromosome 12qF1.
TL;DR: The findings from Northerns and cDNA cloning clarify the genomic organization of this region and expand the number of maternally expressed noncoding RNAs whose loss may be responsible for the phenotypes associated with mouse p UPD12 and human pUPD14 syndromes.
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Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases
Qing Ma,Hansjuerg Alder,Kelly K. Nelson,Devjani Chatterjee,Y. Gu,Tatsuya Nakamura,Eli Canaani,Carlo M. Croce,Linda D. Siracusa,Arthur M. Buchberg +9 more
TL;DR: The cloning, sequencing, and mapping of the mouse homolog of ALL-1 are described and it is reported that All-1 resides in the proximal portion of mouse chromosome 9 and is a candidate for a mutation that results in skeletal transformations during embryonic development.
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MicroRNA genes are frequently located near mouse cancer susceptibility loci
Cinzia Sevignani,George A. Calin,Stephanie C. Nnadi,Masayoshi Shimizu,Ramana V. Davuluri,Terry Hyslop,Peter Demant,Carlo M. Croce,Linda D. Siracusa +8 more
TL;DR: A statistically significant association between the chromosomal location of miRNAs and those of mouse cancer susceptibility loci that influence the development of solid tumors is reported, which provides a catalog of miRNA genes in inbred strains that could represent genes involved in the development and penetrance ofSolid tumors.