C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis
Tamotsu Kuroki,Sai Yendamuri,Francesco Trapasso,Ayumi Matsuyama,Rami I. Aqeilan,Hansjuerg Alder,Shashi Rattan,Rossano Cesari,Maria L. Nolli,Noel N. Williams,Masaki Mori,Takashi Kanematsu,Carlo M. Croce +12 more
TL;DR: The results indicate that the WWOX gene may play an important role in pancreatic tumor development.
Journal ArticleDOI
Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma
Gustavo Baldassarre,Sabrina Battista,Sabrina Battista,Barbara Belletti,Sanjay Thakur,Francesca Pentimalli,Francesca Pentimalli,Francesco Trapasso,Monica Fedele,Giovanna Maria Pierantoni,Carlo M. Croce,Alfredo Fusco +11 more
TL;DR: It is reported that both in vitro and in vivo HMGA1b protein binds to and inhibits the activity of both human and mouse BRCA1 promoters, and their overexpression may have a role in BrcA1 downregulation observed in aggressive mammary carcinomas.
Journal ArticleDOI
Disrupted microRNA expression caused by Mecp2 loss in a mouse model of Rett syndrome
Rocío G. Urdinguio,Agustín F. Fernández,Pilar López-Nieva,Simona Rossi,Dori Huertas,Marta Kulis,Chang Gong Liu,Carlo M. Croce,George A. Calin,Manel Esteller +9 more
TL;DR: It is observed that the brain of Rett syndrome mice undergoes a disruption of the expression profiles of miRNAs, and overall downregulation of these transcripts was the most common feature, whilst the remaining 30% were upregulated.
Journal ArticleDOI
Mutational landscape of gastric adenocarcinoma in Chinese: implications for prognosis and therapy.
Kexin Chen,Da Yang,Da Yang,Xiangchun Li,Xiangchun Li,Baocun Sun,Fengju Song,Wenfeng Cao,Daniel J. Brat,Zhibo Gao,Haixin Li,Han Liang,Yanrui Zhao,Hong Zheng,Miao Li,Jan C. Buckner,Scott D. Patterson,Xiang Ye,Christoph Reinhard,Anahita Bhathena,Deepa Joshi,Paul S. Mischel,Carlo M. Croce,Yi Michael Wang,Sreekumar Raghavakaimal,Hui Li,Xin Lu,Yang Pan,Han Chang,Sujuan Ba,Longhai Luo,Longhai Luo,Webster K. Cavenee,Wei Zhang,Xishan Hao +34 more
TL;DR: Wang et al. as discussed by the authors performed whole-exome sequencing on 78 GCs of differing histologies and anatomic locations, as well as whole-genome sequencing for two GC cases, each with three primary tumors and two matching lymph node metastases.
Journal ArticleDOI
Loss of WWOX Expression in Gastric Carcinoma
Rami I. Aqeilan,Tamotsu Kuroki,Yuri Pekarsky,Omar M. E. Albagha,Francesco Trapasso,Raffaele Baffa,Kay Huebner,Pamela Edmonds,Carlo M. Croce +8 more
TL;DR: The results indicate that alterations of the WWOX gene may be involved quite frequently in gastric tumorigenesis, and could be used in future studies to develop diagnostic and targeted therapy of stomach cancer.