C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Suppression of production of mouse 28S ribosomal RNA in mouse-human hybrids segregating mouse chromosomes
TL;DR: Mouse-human somatic cell hybrids that lose (segregate) human chromosomes produce only mouse 28S ribosomal RNA even when they retain copies of the human chromosomes that contain the genes for 28S ribsomal RNA.
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miR-579-3p controls melanoma progression and resistance to target therapy
Luigi Fattore,Rita Mancini,Mario Acunzo,Giulia Romano,Alessandro Laganà,Maria Elena Pisanu,Debora Malpicci,Gabriele Madonna,Domenico Mallardo,M. Capone,Franco Fulciniti,Luca Mazzucchelli,Gerardo Botti,Carlo M. Croce,Paolo A. Ascierto,Gennaro Ciliberto +15 more
TL;DR: A previously poorly characterized miRNA, namely miR-579-3p, is identified as a master regulator of melanoma progression and drug resistance and is strongly down-regulated in matched tumor samples from patients before and after the development of resistance to targeted therapies.
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Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway.
Gustavo Baldassarre,Monica Fedele,Sabrina Battista,Andrea Vecchione,Andres J. Klein-Szanto,Massimo Santoro,Thomas A. Waldmann,Nazli Azimi,Carlo M. Croce,Alfredo Fusco +9 more
TL;DR: It is reported that HMGI-C/T TG mice develop natural killer (NK)-T/NK cell lymphomas starting from 12 months of age, and it is demonstrated that HM GI-C-T protein positively regulates their expression in vitro.
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p62/SQSTM1 synergizes with autophagy for tumor growth in vivo
TL;DR: It is demonstrated that p62 and autophagy synergize to promote tumor growth, suggesting that inhibition of both pathways could be more effective than targeting either alone for cancer therapy.
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MicroRNA-31 Predicts the Presence of Lymph Node Metastases and Survival in Patients with Lung Adenocarcinoma
Wei Meng,Zhenqing Ye,Ri Cui,Ri Cui,James Perry,Vaia Dedousi-Huebner,Alexander Huebner,Yao Wang,Bin Li,Stefano Volinia,Hiroshi Nakanishi,Taewan Kim,Sung Suk Suh,Leona W. Ayers,Patrick Ross,Carlo M. Croce,Arnab Chakravarti,Victor X. Jin,Tim Lautenschlaeger +18 more
TL;DR: In vitro functional assays showed that miR-31 increases cell migration, invasion, and proliferation in an ERK1/2 signaling-dependent manner and potentially identified a miRNA predicting the presence of lymph node metastasis and survival outcomes in patients of lung adenocarcinoma.