C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans
Yuri Pekarsky,Manuela Campiglio,Zurab Siprashvili,Teresa Druck,Yurii Sedkov,Sergei Tillib,A. Draganescu,Peter J. Wermuth,Joel H. Rothman,Kay Huebner,Arthur M. Buchberg,Alexander Mazo,Charles Brenner,Carlo M. Croce +13 more
TL;DR: It is postulate that Fhit and Nit1 likewise collaborate in a biochemical or cellular pathway in mammalian cells.
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The Role of microRNAs in the Tumorigenesis of Ovarian Cancer.
Gianpiero Di Leva,Carlo M. Croce +1 more
TL;DR: Given the heterogeneity of this disease, it is likely that increases in long-term survival might be also achieved by translating the recent insights of miRNAs involvement in EOC into novel targeted therapies that will have a major impact on the management of ovarian cancer.
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MicroRNAs in diseases and drug response.
TL;DR: This review of miRNA profiling studies in human diseases and the newly discovered link between microRNAs and drug response will be of key importance in developing drugs with greater safety and efficacy.
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ROR1 can interact with TCL1 and enhance leukemogenesis in Eμ-TCL1 transgenic mice.
George F. Widhopf,Bing Cui,Emanuela M. Ghia,Liguang Chen,Karen Messer,Zhouxin Shen,Steven P. Briggs,Carlo M. Croce,Thomas J. Kipps +8 more
TL;DR: This study demonstrates that ROR1 can contribute to leukemogenesis and can bind to T-cell leukemia 1 (TCL1), a known coactivator of AKT, and accelerates development/progression of leukemia and may be targeted for therapy of patients with CLL.
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Self-fusion of the ALL1 gene. A new genetic mechanism for acute leukemia.
TL;DR: The most significant of these genetic findings involves the ALL1 gene, which participates in acute leukemias in 5% to 10% of children and adults, and was discovered by its association with well-characterized chromosomal rearrangements.