C
Carlos Bustamante
Researcher at Stanford University
Publications - 799
Citations - 122303
Carlos Bustamante is an academic researcher from Stanford University. The author has contributed to research in topics: Population & DNA. The author has an hindex of 161, co-authored 770 publications receiving 106053 citations. Previous affiliations of Carlos Bustamante include Lawrence Berkeley National Laboratory & University of California.
Papers
More filters
Posted ContentDOI
Population Genetic Analysis of the DARC Locus (Duffy) Reveals Adaptation from Standing Variation Associated with Malaria Resistance in Humans
Kimberly F. McManus,Angela M. Taravella,Brenna M. Henn,Carlos Bustamante,Martin Sikora,Omar E. Cornejo +5 more
TL;DR: The evolutionary history of a gene associated with resistance to the most common malaria-causing parasite, Plasmodium vivax, is revisited and it is shown that it is one of regions of the human genome that has been under strongest selective pressure in the authors' evolutionary history.
Supplementary Information for: The genetic prehistory of southern Africa
Joseph K. Pickrell,Nick Patterson,Chiara Barbieri,Falko Berthold,Linda Gerlach,Blesswell Kure,Hirosi Nakagawa,Christfried Naumann,Mark Lipson,Po-Ru Loh,Joseph Lachance,Joanna L. Mountain,Carlos Bustamante,Bonnie Berger,Sarah Tishko,Brenna M. Henn,Mark Stoneking,David Reich,Brigitte Pakendorf +18 more
TL;DR: This paper aims to demonstrate the efforts towards in-situ applicability of the MPI for Evolutionary Anthropology, as to provide real-time information about an individual’s TSP.
Journal ArticleDOI
Structural Variation Detection by Proximity Ligation from Formalin-Fixed, Paraffin-Embedded Tumor Tissue
Christopher J. Troll,Nicholas H. Putnam,Paul D. Hartley,Brandon J. Rice,Marco Blanchette,Sameed Siddiqui,Javkhlan-Ochir Ganbat,Martin P. Powers,Ramesh Ramakrishnan,Christian A. Kunder,Carlos Bustamante,James L. Zehnder,Richard E. Green,Helio A. Costa +13 more
TL;DR: A high-throughput chromosome conformation capture approach for FFPE samples that is similar in concept to Hi-C and will enable detailed resolution of global genome rearrangement events during cancer progression from FFPEs and will inform the development of targeted molecular diagnostic assays for patient care.
Journal ArticleDOI
Mechanical, electrical, and chemical manipulation of single DNA molecules
Jiang Yuqiu,Ching-Bo Juang,David Keller,Carlos Bustamante,David Beach,T.W. Houseal,E. Builes +6 more
TL;DR: The results presented represent a first step in the development of molecular scale surgery on cells and organelles and the use of polymers to fabricate molecular scale structures and devices.
Proceedings ArticleDOI
LitGen: Genetic Literature Recommendation Guided by Human Explanations.
Allen Nie,Arturo Lopez Pineda,Matthew Wright,Hannah Wand,Bryan Wulf,Helio A. Costa,Ronak Y. Patel,Carlos Bustamante,James Zou +8 more
TL;DR: This work proposes the first machine learning system, LitGen, that can retrieve papers for a particular variant and filter them by specific evidence types used by curators to assess for pathogenicity, and uses semi-supervised deep learning to predict the type of evidence provided by each paper.