C
Carlos Bustamante
Researcher at Stanford University
Publications - 799
Citations - 122303
Carlos Bustamante is an academic researcher from Stanford University. The author has contributed to research in topics: Population & DNA. The author has an hindex of 161, co-authored 770 publications receiving 106053 citations. Previous affiliations of Carlos Bustamante include Lawrence Berkeley National Laboratory & University of California.
Papers
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Journal ArticleDOI
RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP
Sophie Dumont,Wei Cheng,Victor Serebrov,Rudolf K. F. Beran,Ignacio Tinoco,Anna Marie Pyle,Carlos Bustamante +6 more
TL;DR: This work follows in real time, at a resolution of two base pairs and 20 ms, the RNA translocation and unwinding cycles of a hepatitis C virus helicase (NS3) monomer, a representative superfamily-2 helicase essential for viral replication, and therefore a potentially important drug target.
Journal ArticleDOI
Genetic Architecture of Aluminum Tolerance in Rice (Oryza sativa) Determined through Genome-Wide Association Analysis and QTL Mapping
Adam N. Famoso,Keyan Zhao,Randy T. Clark,Chih-Wei Tung,Mark Wright,Carlos Bustamante,Leon V. Kochian,Susan R. McCouch +7 more
TL;DR: The hypothesis that selectively introgressing alleles across subpopulations is an efficient approach for trait enhancement in plant breeding programs is supported and demonstrates the fundamental importance of subpopulation in interpreting and manipulating the genetics of complex traits in rice.
Journal ArticleDOI
Single-molecule study of transcriptional pausing and arrest by E. coli RNA polymerase.
TL;DR: The studies reveal that RNA polymerase molecules possess different intrinsic transcription rates and different propensities to pause and stop, and show that reversible pausing is a kinetic intermediate between normal elongation and the arrested state.
Molecular and Evolutionary History of Melanism in North
Tovi M. Anderson,Bridgett M. vonHoldt,Sophie I. Candille,Marco Musiani,Claudia Greco,Daniel R. Stahler,Douglas W. Smith,Badri Padhukasahasram,Ettore Randi,Jennifer A. Leonard,Carlos Bustamante,Elaine A. Ostrander,Hua Tang,Robert K. Wayne,Gregory S. Barsh +14 more
TL;DR: It is shown that the melanistic K locus mutation in North American wolves derives from past hybridization with domestic dogs, has risen to high frequency in forested habitats, and exhibits a molecular signature of positive selection.
Book ChapterDOI
Optical-trap force transducer that operates by direct measurement of light momentum.
TL;DR: The optical-trap force transducer that operates by the direct measurement of light momentum is described, which is useful in molecular and cell biology because several important forces are in an accessible piconewton (pN) range.