C
Carlos Bustamante
Researcher at Stanford University
Publications - 799
Citations - 122303
Carlos Bustamante is an academic researcher from Stanford University. The author has contributed to research in topics: Population & DNA. The author has an hindex of 161, co-authored 770 publications receiving 106053 citations. Previous affiliations of Carlos Bustamante include Lawrence Berkeley National Laboratory & University of California.
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Journal ArticleDOI
High Degree of Coordination and Division of Labor among Subunits in a Homomeric Ring ATPase
Gheorghe Chistol,Shixin Liu,Craig L. Hetherington,Jeffrey R. Moffitt,Shelley Grimes,Paul J. Jardine,Carlos Bustamante,Carlos Bustamante +7 more
TL;DR: A comprehensive mechanochemical characterization of a homomeric ring ATPase-the bacteriophage φ29 packaging motor-a homopentamer that translocates double-stranded DNA in cycles composed of alternating dwells and bursts and shows that the motor displays an unexpected division of labor.
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Gut microbiome transition across a lifestyle gradient in Himalaya.
Aashish R. Jha,Emily R. Davenport,Yoshina Gautam,Dinesh Bhandari,Sarmila Tandukar,Katharine M. Ng,Gabriela K. Fragiadakis,Susan Holmes,Guru Prasad Gautam,Jeff Leach,Sherchand Jb,Carlos Bustamante,Justin L. Sonnenburg +12 more
TL;DR: The gut microbiomes of Raute and Raji reveal an intermediate state between the Chepang and Tharu, indicating that divergence from a stereotypical foraging microbiome can occur within a single generation, and environmental factors such as drinking water source and solid cooking fuel are significantly associated with the gut microbiome.
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The Optical Activity of Nucleic Acids and their Aggregates
TL;DR: This review includes experimental and theoretical work on absorption and scattering of light by chiral macromolecules, and theoretical methods that relate the absorption and circular dichroism of a polymer or aggregate to the optical proper ties of its constituent parts.
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A two-state kinetic model for the unfolding of single molecules by mechanical force
TL;DR: The model yields estimates for parameters that characterize the unfolding kinetics under force in agreement with those obtained in recent experimental results, and a general equation for the minimum number of repeated experiments needed to obtain an equilibrium free energy, to within kBT, from nonequilibrium experiments is obtained.
Journal ArticleDOI
Proofreading dynamics of a processive DNA polymerase
Borja Ibarra,Yann R. Chemla,Sergey Plyasunov,Steven B. Smith,José M. Lázaro,Margarita Salas,Carlos Bustamante +6 more
TL;DR: It is found that mechanical tension applied to a single polymerase–DNA complex promotes the intramolecular transfer of the primer in a similar way to the incorporation of a mismatched nucleotide.