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Carlos Bustamante
Researcher at Stanford University
Publications - 799
Citations - 122303
Carlos Bustamante is an academic researcher from Stanford University. The author has contributed to research in topics: Population & DNA. The author has an hindex of 161, co-authored 770 publications receiving 106053 citations. Previous affiliations of Carlos Bustamante include Lawrence Berkeley National Laboratory & University of California.
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Measurement of the Effect of Monovalent Cations on RNA Hairpin Stability
TL;DR: Using optical tweezers, the effect of monovalent cation concentration and species on the folding free energy of five large RNA hairpins, including HIV-1 TAR and molecules approximating A.U and G.C.C homopolymers is measured.
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Differential scattering of circularly polarized light by the helical sperm head from the octopus Eledone cirrhosa
TL;DR: In this paper, the authors measured the differential scattering of left and right circularly polarized light from the sperm head of the octopus Eledone cirrhosa, which is a left-handed helix with pitch and diameter of about 1 µm.
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Absorption, Scattering, and Imaging of Biomolecular Structures with Polarized Light
TL;DR: This research presents a new perspective on the interaction of light and matter through the lens of circular dichroism, which has implications for knowledge of natural disasters and human evolution.
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Direct measurement of the mechanical work during translocation by the ribosome
Tingting Liu,Ariel Kaplan,Lisa Alexander,Shannon Yan,Jin-Der Wen,Laura Lancaster,Charles E. Wickersham,Kurt Fredrick,Harry F. Noller,Ignacio Tinoco,Carlos Bustamante +10 more
TL;DR: It is found that translocation rates depend exponentially on the force, with a characteristic distance close to the one-codon step, ruling out the existence of sub-steps and showing that the ribosome likely functions as a Brownian ratchet, thus providing a basis for their regulatory role.
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Molecular mechanisms of transcription through single-molecule experiments.
TL;DR: During transcription, a DNA molecule is copied into RNA molecules that are then used to translate the genetic information into proteins; this logical pattern has been conserved throughout all three kingdoms of life, making it an essential and fundamental cellular process.