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Carlos Bustamante

Researcher at Stanford University

Publications -  799
Citations -  122303

Carlos Bustamante is an academic researcher from Stanford University. The author has contributed to research in topics: Population & DNA. The author has an hindex of 161, co-authored 770 publications receiving 106053 citations. Previous affiliations of Carlos Bustamante include Lawrence Berkeley National Laboratory & University of California.

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Detecting coevolving amino acid sites using Bayesian mutational mapping

TL;DR: Results on simulated coevolutionary data indicate that the BMM method can successfully detect nearly all coevolving sites when the model has been correctly specified, and that non-parametric statistics such as mutual information are generally less powerful than parametric statistics.
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Copy number variation of CCL3-like genes affects rate of progression to simian-AIDS in Rhesus Macaques (Macaca mulatta).

TL;DR: It is suggested that stratification by CCL3L copy number in rhesus SIV vaccine trials will increase power and reduce noise due to non-vaccine-related differences in survival, and CCL 3L CNV is an ancestral component of the primate immune response and, therefore, copy number variation has not been driven by HIV or SIV per se.
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Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

Michelle Daya, +65 more
TL;DR: A genome-wide meta-analysis from the Consortium on Asthma among African Ancestry Populations (CAAPA) finds strong evidence for association at four previously reported asthma loci and identifies two potentially African ancestry-specific loci that may be specific to asthma risk in African ancestry populations.
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The psi‐type circular dichroism of large molecular aggregates. III. Calculations

TL;DR: In this paper, it was shown that the radiation and intermediate couplings between the chromophores in the aggregates played an important role in determining the shape and magnitude of the psi-type CD spectrum.
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Optimized two-color super resolution imaging of Drp1 during mitochondrial fission with a slow-switching Dronpa variant

TL;DR: A slow-switching Dronpa variant, rsKame, featuring a V157L amino acid substitution proximal to the chromophore reduced the excitation light-induced photoactivation from the dark to fluorescent state, suggesting support for the twistase model of Drp1 constriction, with potential loss of subunits at the helical ends.