C
Carlos Bustamante
Researcher at Stanford University
Publications - 799
Citations - 122303
Carlos Bustamante is an academic researcher from Stanford University. The author has contributed to research in topics: Population & DNA. The author has an hindex of 161, co-authored 770 publications receiving 106053 citations. Previous affiliations of Carlos Bustamante include Lawrence Berkeley National Laboratory & University of California.
Papers
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Journal ArticleDOI
North African Jewish and non-Jewish populations form distinctive, orthogonal clusters
Christopher L. Campbell,Pier Francesco Palamara,Maya Dubrovsky,Laura R. Botigué,Marc Fellous,Gil Atzmon,Carole Oddoux,Alexander Pearlman,Li Hao,Brenna M. Henn,Edward R. Burns,Carlos Bustamante,David Comas,Eitan Friedman,Itsik Pe'er,Harry Ostrer +15 more
TL;DR: This study is compatible with the history of North African Jews—founding during Classical Antiquity with proselytism of local populations, followed by genetic isolation with the rise of Christianity and then Islam, and admixture following the emigration of Sephardic Jews during the Inquisition.
Journal ArticleDOI
Xrare: a machine learning method jointly modeling phenotypes and genetic evidence for rare disease diagnosis
TL;DR: The Xrare model is learned from a large database of clinical variants, and derives its strength from the tight integration of medical genetics features and phenotypic features similarity scores.
Journal ArticleDOI
Helically organized macroaggregates of pigment-protein complexes in chloroplasts: evidence from circular intensity differential scattering
TL;DR: Modeling of the CIDS data by a simple helical array of uniaxial polarizable groups suggests that the chiral structure is left-handed with pitch and radius of the order of 385 nm.
Journal ArticleDOI
Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans.
Roxana Daneshjou,Eric R. Gamazon,Ben Burkley,Larisa H. Cavallari,Julie A. Johnson,Teri E. Klein,Nita A. Limdi,Sara Hillenmeyer,Bethany Percha,Konrad J. Karczewski,Taimour Y. Langaee,Shitalben R. Patel,Carlos Bustamante,Russ B. Altman,Minoli A. Perera +14 more
TL;DR: The results provide the first evidence linking genetic variation in folate homeostasis to warfarin response, and a population-specific regulatory variant, rs7856096, which overlaps functional elements and was associated with FPGS gene expression in lymphoblastoid cell lines derived from combined HapMap African populations.
Patent
Compositions and methods for targeted depletion, enrichment, and partitioning of nucleic acids using crispr/cas system proteins
TL;DR: In this paper, methods and compositions for depleting targeted nucleic acid sequences from a sample, enriching for sequences of interest from a sampled sample, and/or partitioning of sequences are presented.