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Carlos Centeno

Bio: Carlos Centeno is an academic researcher from University of Navarra. The author has contributed to research in topics: Palliative care & Medicine. The author has an hindex of 31, co-authored 171 publications receiving 3647 citations. Previous affiliations of Carlos Centeno include NHS Dumfries and Galloway & University of Texas MD Anderson Cancer Center.


Papers
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TL;DR: The greatest challenge faced by the core group was trying to find a middle ground between those who think that PC is the relief of all suffering and those who believe that PC describes the care of those with a very limited remaining life span.

332 citations

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TL;DR: In this article, the authors present a review of the process of validating an instrument for measuring health, and what it involves, in a practical way, and the accessibility of evaluation instruments that have been adapted and validated in different languages will facilitate the comparison of results obtained with the same instrument and the development international studies in different cultures.
Abstract: It is increasingly necessary to have a measuring instrument available in the health field that can be used in clinical practice and research. In order to guarantee the quality of their measurements it is essential that the instruments should be subjected to a process of validation. This process consists in adapting the instrument culturally to the setting where its psychometric characteristics are to be administered and checked, such as: reliability, validity, sensitivity and feasibility. There are measuring instruments from the health field available in other languages but that have not been validated into Spanish. Besides, the methodology for validating an instrument is little understood by the health professionals, which explains the indiscriminate use of instruments that have only been adapted or validated in a way that is not very consistent. The aim of this review is to bring up to date the process of validating an instrument for measuring health, and what it involves, in a practical way. The accessibility of evaluation instruments that have been culturally adapted and validated in different languages will facilitate the comparison of results obtained with the same instrument and the development international studies in different cultures.

270 citations

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TL;DR: The key policy and educational opportunities in the United States to address and potentially overcome the barriers to greater integration of palliative care into the healthcare of Americans with serious illness are described.
Abstract: Background:Early integration of palliative care into the management of patients with serious disease has the potential to both improve quality of life of patients and families and reduce healthcare...

244 citations

Journal ArticleDOI
TL;DR: The primary therapeutic approach is to identify the reversible causes of delirium and some therapeutic strategies have been shown to be effective: reduction or withdrawal of the psychoactive medication, opioid rotation, and hydration.
Abstract: Delirium in advanced cancer is often poorly identified and inappropriately managed. It is one of the most common causes for admission to clinical institutions and is the most frequently cited psychiatric disorder in terminal cancer. Diagnosis of delirium is defined as a disturbance of consciousness and attention with a change in cognition and/or perception. In addition, it develops suddenly and follows a fluctuating course and it is related to other causes, such as cancer, metabolic disorders or the effects of drugs. Delirium occurs in 26% to 44% of cancer patients admitted to hospital or hospice. Of all advanced cancer patients, over 80% eventually experience delirium in their final days. In advanced cancer, delirium is a multifactorial syndrome where opioids factor in almost 60% of episodes. Delirium in such patients, excluding terminal delirium, may be reversible in 50% of cases. Providing adequate end-of-life care for a patient with delirium is the main challenge. The family needs advice and it is important to create a relaxing environment for the patient. The primary therapeutic approach is to identify the reversible causes of delirium. Some therapeutic strategies have been shown to be effective: reduction or withdrawal of the psychoactive medication, opioid rotation, and hydration. Haloperidol is the most frequently used drug, and new neuroleptics such as risperidone or olanzapine are being tested with good results. Methylphenidate has been used for hypoactive delirium.

190 citations


Cited by
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TL;DR: Despite increased attention on assessment and management, pain continues to be a prevalent symptom in patients with cancer and in the upcoming decade, the authors need to overcome barriers toward effective pain treatment and develop and implement interventions to optimally manage pain in Patients with cancer.

1,059 citations

Journal ArticleDOI

787 citations