Carmel Hayes

TL;DR: The results clearly indicate that the proposed nonrigid registration algorithm is much better able to recover the motion and deformation of the breast than rigid or affine registration algorithms.

TL;DR: Investigation of correlations between qualitatative and quantitative methods of analysis for DCE‐MR images from breast cancer patients undergoing neo‐adjuvant chemotherapy found changes in the rate of enhancement correlated strongly with changes in Ktrans values, and it was found that the shape of the signal enhancement curve only changed when the K trans values changed by 50% or more.

TL;DR: Reductions in MR imaging-determined size of the primary tumor best predict clinicopathologic response of breast cancer after one cycle of neoadjuvant chemotherapy.

TL;DR: Fat and the femoral head are unreliable tissues from which to obtain kinetic parameter estimates due to poor enhancement and Reproducibility studies of normal and pathological tissues should be incorporated into clinical research protocols that measure treatment effects by DCE‐MRI techniques.

TL;DR: Nonrigid registration significantly reduces the effects of movement artifact in subtracted contrast-enhanced breast MRI, which may enable better visualization of small tumors and those within a glandular breast.