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Carmelo De Maria

Researcher at University of Pisa

Publications -  118
Citations -  1788

Carmelo De Maria is an academic researcher from University of Pisa. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 14, co-authored 88 publications receiving 1066 citations.

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In vivo assessment of printed microvasculature in a bilayer skin graft to treat full-thickness wounds.

TL;DR: A dermo-epidermal graft has been implanted in an athymic nude mouse model to assess the integration with the host tissue as well as the wound healing process and immunohistochemistry analysis showed favorable results proving survival of the implanted cells.
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Endothelial cells support osteogenesis in an in vitro vascularized bone model developed by 3D bioprinting.

TL;DR: An in vitro vascularized bone model, using a gelatin-nanohydroxyapatite (gel-nHA) 3D bioprinted scaffold, simulating de novo morphogenesis of capillary vessels occurring during tissue development and highlighting how the inclusion of endothelial cells more realistically supports osteogenesis is highlighted.
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Substrate stiffness influences high resolution printing of living cells with an ink-jet system.

TL;DR: The computational model and the experimental results confirm that impact forces are highly dependent on the deposition substrate and that soft and viscous surfaces can reduce the forces acting on the droplet, preventing cell damage.
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An autologously generated platelet-rich plasma suturable membrane may enhance peripheral nerve regeneration after neurorraphy in an acute injury model of sciatic nerve neurotmesis.

TL;DR: The data show that the application of a PRP fibrin membrane around the neurorraphy improves the nerve regeneration process in a rat sciatic nerve model and could perform an action not only as a source of bioactive proteins but also as a nerve guide to hold the scar reaction and thus improve axonal regeneration.