Carmen Alvarez-Lorenzo

TL;DR: In this review, the mechanisms used to develop polymeric micelles, gels, liposomes and nanocomposites with light‐sensitiveness are analyzed and the potential of light‐sensitive carriers as functional components of intelligent DDS is discussed.

TL;DR: The state of the art of crosslinked ionic polysaccharides as components of delivery systems that can regulate drug release as a function of changes in pH, ion nature and concentration, electric and magnetic field intensity, light wavelength, temperature, redox potential, and certain molecules are analyzed.

TL;DR: This review seeks to highlight the more remarkable advantages of the imprinting technique in the development of new efficient DDS as well as pointing out some possibilities to adapt the synthesis procedures to create systems compatible with both the relative instable drug molecules and the sensitive physiological tissues with which MIP-based DDS would enter into contact when administered.

TL;DR: A critical overview of therapeutically-interesting stimuli to trigger drug release and the evolution of responsive materials suitable as functional excipients is offered, illustrated with recent examples of formulations in clinical trials or already commercially available, which can provide a perspective on the current state of the art on smart drug delivery systems.

TL;DR: Results indicate that imprinted soft contact lenses are promising drug devices able to provide greater and more sustained drug concentrations in tear fluid with lower doses than conventional eyedrops.