C
Carmen Urbich
Researcher at Goethe University Frankfurt
Publications - 96
Citations - 25642
Carmen Urbich is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Endothelial stem cell & Progenitor cell. The author has an hindex of 60, co-authored 96 publications receiving 24660 citations.
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Journal ArticleDOI
Endothelial Progenitor Cells: Characterization and Role in Vascular Biology
Carmen Urbich,Stefanie Dimmeler +1 more
TL;DR: This review summarizes the mechanisms regulating endothelial progenitor cell–mediated neovascularization and reendothelialization and describes the characterization of the different progenitors cell populations.
Journal ArticleDOI
Number and Migratory Activity of Circulating Endothelial Progenitor Cells Inversely Correlate With Risk Factors for Coronary Artery Disease
Mariuca Vasa,Stephan Fichtlscherer,Alexandra Aicher,Klaudia Adler,Carmen Urbich,Hans Martin,Andreas M. Zeiher,Stefanie Dimmeler +7 more
TL;DR: Patients with CAD revealed reduced levels and functional impairment of EPCs, which correlated with risk factors for CAD, and hypertension was identified as a major independent predictor for impaired EPC migration.
Journal ArticleDOI
Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI)
Birgit Assmus,Volker Schächinger,Claudius Teupe,Martina B. Britten,Ralf Lehmann,N. Döbert,Frank Grünwald,Alexandra Aicher,Carmen Urbich,Hans Martin,Dieter Hoelzer,Stefanie Dimmeler,Andreas M. Zeiher +12 more
TL;DR: In patients with AMI, intracoronary infusion of autologous progenitor cells appears to be feasible and safe and may beneficially affect postinfarction remodeling processes.
Journal ArticleDOI
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells.
Alexandra Aicher,Christopher Heeschen,Christiane Mildner-Rihm,Carmen Urbich,Christian Ihling,Katja Technau-Ihling,Andreas M. Zeiher,S Dimmeler +7 more
TL;DR: It is indicated that eNOS expressed by bone marrow stromal cells influences recruitment of stem and progenitor cells, which may contribute to impaired regeneration processes in ischemic heart disease patients, who are characterized by a reduced systemic NO bioactivity.
Journal ArticleDOI
MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice
Angelika Bonauer,Guillaume Carmona,Masayoshi Iwasaki,Marina Mione,Masamichi Koyanagi,Ariane Fischer,Jana Burchfield,Henrik Fox,Carmen Doebele,Kisho Ohtani,Emmanouil Chavakis,Michael Potente,Marc Tjwa,Carmen Urbich,Andreas M. Zeiher,Stefanie Dimmeler +15 more
TL;DR: It is shown that themiR-17~92 cluster is highly expressed in human endothelial cells and that miR-92a, a component of this cluster, controls the growth of new blood vessels (angiogenesis) and may serve as a valuable therapeutic target in the setting of ischemic disease.