C
Carolina De La Torre
Researcher at Heidelberg University
Publications - 73
Citations - 2001
Carolina De La Torre is an academic researcher from Heidelberg University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 15, co-authored 52 publications receiving 1087 citations. Previous affiliations of Carolina De La Torre include University of Barcelona & Autonomous University of Barcelona.
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Journal ArticleDOI
miRWalk: An online resource for prediction of microRNA binding sites.
TL;DR: The core of miRWalk is the miRNA target site prediction with the random-forest-based approach software TarPmiR searching the complete transcript sequence including the 5’-UTR, CDS and 3’ -UTR.
Journal ArticleDOI
Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program
Maxime Janin,Vanessa Ortiz-Barahona,Manuel Castro de Moura,Anna Martínez-Cardús,Pere Llinàs-Arias,Marta Soler,Daphna Nachmani,Joffrey Pelletier,Ulrike Schumann,Maria E. Calleja-Cervantes,Sebastian Moran,Sonia Guil,Alberto Bueno-Costa,David Piñeyro,Montserrat Pérez-Salvia,Margalida Rosselló-Tortella,Laia Piqué,Joan Josep Bech-Serra,Carolina De La Torre,August Vidal,María Martínez-Iniesta,Juan F. Martín-Tejera,Alberto Villanueva,Alexandra Arias,Isabel Cuartas,Ana M. Aransay,Andres Morales La Madrid,Angel M. Carcaboso,Vicente Santa-Maria,Jaume Mora,Agustín F. Fernández,Mario F. Fraga,Iban Aldecoa,Leire Pedrosa,Francesc Graus,Noemi Vidal,Fina Martínez-Soler,Avelina Tortosa,Cristina Carrato,C. Balana,Matthew W. Boudreau,Paul J. Hergenrother,Peter Kötter,K. D. Entian,Jürgen Hench,Stephan Frank,Sheila Mansouri,Gelareh Zadeh,Pablo D. Dans,Modesto Orozco,George Thomas,George Thomas,Sandra Blanco,Joan Seoane,Joan Seoane,Thomas Preiss,Thomas Preiss,Pier Paolo Pandolfi,Manel Esteller +58 more
TL;DR: It is found that human glioma cells undergo DNA methylation-associated epigenetic silencing of NSUN5, a candidate RNA methyltransferase for 5-methylcytosine, which exhibits tumor-suppressor characteristics in vivo gliomas models and leads to the emergence of an adaptive translational program for survival under conditions of cellular stress.
Journal ArticleDOI
Absence of Dysferlin Alters Myogenin Expression and Delays Human Muscle Differentiation “in Vitro”
Noemi de Luna,Eduard Gallardo,Mario Soriano,R. Dominguez-Perles,Carolina De La Torre,Ricardo Rojas-García,José Manuel García-Verdugo,Isabel Illa +7 more
TL;DR: Results point to a functional link between dysferlin and myogenin, and both proteins may share a new signaling pathway involved in differentiation of skeletal muscle in vitro.
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Human Apolipoprotein A-II Determines Plasma Triglycerides by Regulating Lipoprotein Lipase Activity and High-Density Lipoprotein Proteome
Josep Julve,Joan Carles Escolà-Gil,Noemi Rotllan,Catherine Fievet,Emmanuelle Vallez,Carolina De La Torre,Vicent Ribas,John H. Sloan,Francisco Blanco-Vaca +8 more
TL;DR: ApoA-II plays a crucial role in triglyceride catabolism by regulating LPL activity, at least in part, through HDL proteome modulation.
Journal ArticleDOI
KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer
Laia Simó-Riudalbas,Montserrat Pérez-Salvia,Fernando Setien,Alberto Villanueva,Catia Moutinho,Anna Martínez-Cardús,Sebastian Moran,María Berdasco,Antonio Gomez,Enrique Vidal,Marta Soler,Holger Heyn,Alejandro Vaquero,Carolina De La Torre,Silvia Barceló-Batllori,August Vidal,Luca Roz,Ugo Pastorino,Katalin Szakszon,Guntram Borck,Conceição S. Moura,Fátima Carneiro,Ilse Zondervan,Suvi Savola,Reika Iwakawa,Takashi Kohno,Jun Yokota,Jun Yokota,Manel Esteller,Manel Esteller +29 more
TL;DR: It is demonstrated that KAT6B exerts its tumor-inhibitory role through a newly defined type of histone H3 Lys23 acetyltransferase activity.