C
Caroline J. Voskens
Researcher at University of Erlangen-Nuremberg
Publications - 36
Citations - 1359
Caroline J. Voskens is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Immune system & Immunology. The author has an hindex of 12, co-authored 29 publications receiving 1077 citations. Previous affiliations of Caroline J. Voskens include University of Maryland, Baltimore.
Papers
More filters
Journal ArticleDOI
The Price of Tumor Control: An Analysis of Rare Side Effects of Anti-CTLA-4 Therapy in Metastatic Melanoma from the Ipilimumab Network
Caroline J. Voskens,Simone M. Goldinger,Carmen Loquai,Caroline Robert,Katharina C. Kaehler,Carola Berking,Tanja Bergmann,Clemens L. Bockmeyer,Thomas Eigentler,Michael Fluck,Claus Garbe,Ralf Gutzmer,Stephan Grabbe,Axel Hauschild,Rüdiger Hein,Gheorghe Hundorfean,Armin Justich,Ullrich Keller,Christina Klein,Christine Mateus,Peter Mohr,Sylvie Paetzold,Imke Satzger,Dirk Schadendorf,Marc Schlaeppi,Gerold Schuler,Beatrice Schuler-Thurner,Uwe Trefzer,Jens Ulrich,Julia Vaubel,Roger von Moos,Patrik Weder,Tabea Wilhelm,Daniela Göppner,Reinhard Dummer,Lucie Heinzerling,Lucie Heinzerling +36 more
TL;DR: In this article, a wide spectrum of Ipilimumab-induced adverse events including drug rash with eosinophilia and systemic symptoms (DRESS), granulomatous inflammation of the central nervous system, and aseptic meningitis were documented.
Journal ArticleDOI
Differential effects of α4β7 and GPR15 on homing of effector and regulatory T cells from patients with UC to the inflamed gut in vivo
Anika Fischer,Sebastian Zundler,Raja Atreya,Timo Rath,Caroline J. Voskens,Simon Hirschmann,Rocío López-Posadas,Alastair J.M. Watson,Christoph Becker,Gerold Schuler,Clemens Neufert,Imke Atreya,Markus F. Neurath +12 more
TL;DR: In this article, the in vivo homing of effector (Teff) and regulatory (Treg) T cells to the inflamed gut via α4β7 and G protein receptor GPR15 was analyzed.
Journal ArticleDOI
Fc-dependent expression of CD137 on human NK cells: insights into "agonistic" effects of anti-CD137 monoclonal antibodies.
Wei Lin,Caroline J. Voskens,Xiaoyu Zhang,Daniel Schindler,Aaron Wood,Erin Burch,Yadong Wei,Lieping Chen,Guo-Liang Tian,Koji Tamada,Lai-Xi Wang,Dan H. Schulze,Dean L. Mann,Scott E. Strome +13 more
TL;DR: The data suggest that CD137 can be enhanced on NK cells in an Fc-dependent fashion and that expression correlates with phenotypic and functional parameters of activation.
Journal ArticleDOI
FcγRIIIa polymorphisms and cetuximab induced cytotoxicity in squamous cell carcinoma of the head and neck
Rodney J. Taylor,Siaw Lin Chan,Aaron Wood,Caroline J. Voskens,Jeffrey S. Wolf,Wei Lin,Andrei I. Chapoval,Dan H. Schulze,Guoliang Tian,Scott E. Strome +9 more
TL;DR: The results indicate that SCCHN is susceptible to cetuximab-mediated ADCC in vitro andNK cytotoxic efficiency correlates with donor 158-polymorphisms in FcγRIIIa, and the presence of a V allele correlated with superior natural cytotoxicity against NK sensitive targets.
Journal ArticleDOI
Decreased numbers of regulatory T cells are associated with human atherosclerotic lesion vulnerability and inversely correlate with infiltrated mature dendritic cells.
Barbara Dietel,Iwona Cicha,Caroline J. Voskens,Eric Verhoeven,Stephan Achenbach,Christoph D. Garlichs +5 more
TL;DR: In vulnerable plaques, numbers of total and mature DCs were significantly higher in the inflammatory plaque shoulder, whereas the numbers of Treg were decreased compared to stable plaque, and the association of the observed infiltration rates with plaque stability was confirmed.