C
Carolyn R. Bertozzi
Researcher at Stanford University
Publications - 728
Citations - 69550
Carolyn R. Bertozzi is an academic researcher from Stanford University. The author has contributed to research in topics: Racism & Glycobiology. The author has an hindex of 118, co-authored 691 publications receiving 61006 citations. Previous affiliations of Carolyn R. Bertozzi include University of California, Berkeley & California Institute for Quantitative Biosciences.
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Essentials of Glycobiology
Ajit Varki,Richard D. Cummings,Jeffrey D. Esko,Hudson H. Freeze,Pamela Stanley,Carolyn R. Bertozzi,Gerald W. Hart,Marilynn E. Etzler +7 more
TL;DR: General principles - historical background and overview saccharide structure and nomenclature evolution of glycan diversity protein-glycan Interactions exploring the biological roles of glycans biosynthesis, metabolism, and function.
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Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
TL;DR: The bioorthogonal chemical reactions developed to date are described and how they can be used to study biomolecules.
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A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems
TL;DR: A strain-promoted [3 + 2] cycloaddition between cyclooctynes and azides that proceeds under physiological conditions without the need for a catalyst was demonstrated by selective modification of biomolecules in vitro and on living cells, with no apparent toxicity.
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Cell Surface Engineering by a Modified Staudinger Reaction
Eliana Saxon,Carolyn R. Bertozzi +1 more
TL;DR: A chemical transformation that permits the selective formation of covalent adducts among richly functionalized biopolymers within a cellular context is presented and should permit its execution within a cell's interior, offering new possibilities for probing intracellular interactions.
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Copper-free click chemistry for dynamic in vivo imaging
Jeremy M. Baskin,Jennifer A. Prescher,Scott T. Laughlin,Nicholas J. Agard,Pamela V. Chang,Isaac A. Miller,Anderson Lo,Julian A. Codelli,Carolyn R. Bertozzi +8 more
TL;DR: A Cu-free variant of click chemistry that can label biomolecules rapidly and selectively in living systems, overcoming the intrinsic toxicity of the canonical Cu-catalyzed reaction is reported.