Carsten Janke

TL;DR: Using the provided cassettes for N‐ and C‐terminal gene tagging or for deletion of any given gene, a set of only four primers is required, which makes this method very cost‐effective and reproducible.

TL;DR: IPL1 function in cells that cannot replicate their chromosomes but nevertheless duplicate their spindle pole bodies (SPBs) is investigated and the possibility that Ipl1-Sli15 facilitates bi-orientation by promoting turnover of kinetochore-SPB connections until traction of sister Kinetochores toward opposite spindle poles creates tension in the surrounding chromatin is raised.

TL;DR: Functional studies demonstrating that post-translational modifications may regulate microtubule functions through an amazing range of mechanisms are demonstrated.

TL;DR: This work has shed light on how posttranslational modifications of tubulin could contribute to a “tubulin code” that coordinates the complex functions of microtubules in cells.

TL;DR: This work discusses how tubulin isotypes and post-translational modifications control microtubule behaviour at the molecular level and how this translates into physiological functions at the cellular and organism levels, and shows how fine-tuning of microtubules function by some tubulin modifications can affect homeostasis.