C
Caterina Marchiò
Researcher at University of Turin
Publications - 194
Citations - 7385
Caterina Marchiò is an academic researcher from University of Turin. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 38, co-authored 158 publications receiving 5797 citations. Previous affiliations of Caterina Marchiò include The Breast Cancer Research Foundation & Curie Institute.
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Journal ArticleDOI
FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer
Nicholas C. Turner,Alex Pearson,Rachel Sharpe,Maryou B K Lambros,Felipe C. Geyer,María Ángeles López-García,Rachael Natrajan,Caterina Marchiò,Elizabeth Iorns,Alan Mackay,Cheryl Gillett,Anita Grigoriadis,Andrew Tutt,Jorge S. Reis-Filho,Alan Ashworth +14 more
TL;DR: The data suggest that amplification and overexpression of FGFR1 may be a major contributor to poor prognosis in luminal-type breast cancers, driving anchorage-independent proliferation and endocrine therapy resistance.
Journal ArticleDOI
Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients
David S.P. Tan,Caterina Marchiò,Robin L. Jones,Kay Savage,Ian E. Smith,Mitch Dowsett,Jorge S. Reis-Filho +6 more
TL;DR: Despite treatment with standard dose anthracycline-based chemotherapy, the clinical outcome of TN and BL cancers remains poor and alternative chemotherapeutic regimens and/or novel therapeutic approaches are warranted.
Journal ArticleDOI
Breast cancer precursors revisited: molecular features and progression pathways.
María Ángeles López-García,Felipe C. Geyer,Magali Lacroix-Triki,Caterina Marchiò,Jorge S. Reis-Filho +4 more
TL;DR: Breast cancer precursors revisited: molecular features and progression pathways revisited.
Journal ArticleDOI
ESMO recommendations on the standard methods to detect NTRK fusions in daily practice and clinical research.
Caterina Marchiò,Maurizio Scaltriti,Marc Ladanyi,Anthony J. Iafrate,Frédéric Bibeau,Manfred Dietel,Jaclyn F. Hechtman,Teresa Troiani,Fernando Lopez-Rios,J.-Y. Douillard,Fabrice Andre,Jorge S. Reis-Filho +11 more
TL;DR: Recommendations for the routine clinical detection of targetable NTRK1/2/3 fusions are presented and the choice of assays for screening and final diagnosis should also take into account the resources and clinical context.
Journal ArticleDOI
Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis†
Caterina Marchiò,Maryou B K Lambros,Patrizia Gugliotta,Ludovica Verdun di Cantogno,Cristina Botta,Barbara Pasini,David S.P. Tan,Alan Mackay,Kerry Fenwick,Narinder Tamber,Gianni Bussolati,Alan Ashworth,Jorge S. Reis-Filho,Anna Sapino +13 more
TL;DR: The results suggest that true chromosome 17 polysomy is likely to be a rare event in breast cancer and that CEP17 copy number greater than 3.0 in FISH analysis is frequently related to gain or amplification of the centromeric region.