C
Catharine I. Paules
Researcher at Penn State Milton S. Hershey Medical Center
Publications - 20
Citations - 3180
Catharine I. Paules is an academic researcher from Penn State Milton S. Hershey Medical Center. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 10 publications receiving 1764 citations. Previous affiliations of Catharine I. Paules include Pennsylvania State University.
Papers
More filters
Journal ArticleDOI
Coronavirus Infections-More Than Just the Common Cold.
TL;DR: Yet another pathogenic HCoV, 2019 novel coronavirus (2019-nCoV), was recognized in Wuhan, China, and has caused serious illness and death, and the ultimate scope and effect of this outbreak is unclear at present.
Journal ArticleDOI
Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19.
Andre C. Kalil,Thomas F. Patterson,Aneesh K. Mehta,Kay M. Tomashek,Cameron R. Wolfe,Varduhi Ghazaryan,Vincent C. Marconi,Guillermo M. Ruiz-Palacios,Lanny Hsieh,Susan Kline,Victor F. Tapson,Nicole M. Iovine,Mamta K. Jain,Daniel A. Sweeney,Hana M. El Sahly,Angela Branche,Justino Regalado Pineda,David C. Lye,Uriel Sandkovsky,Anne F Luetkemeyer,Stuart H. Cohen,Robert W. Finberg,Patrick E. H. Jackson,Babafemi Taiwo,Catharine I. Paules,Henry Arguinchona,Nathaniel B. Erdmann,Neera Ahuja,Maria G. Frank,Myoung Don Oh,Eu-Suk Kim,Seow Y Tan,Richard A. Mularski,Henrik Nielsen,Philip O Ponce,Barbara S. Taylor,LuAnn Larson,Nadine Rouphael,Youssef Saklawi,Valeria D Cantos,Emily R Ko,John J. Engemann,Alpesh Amin,Miki Watanabe,Joanne Billings,Marie-Carmelle Elie,Richard T. Davey,Timothy Burgess,Jennifer Ferreira,Michelle Green,Mat Makowski,Anabela Cardoso,Stephanie de Bono,Tyler Bonnett,Michael A. Proschan,Gregory A. Deye,Walla Dempsey,Seema U Nayak,Lori E. Dodd,John H. Beigel +59 more
TL;DR: Baricitinib plus remdesivir was superior to remdes Vivir alone in reducing recovery time and accelerating improvement in clinical status among patients with Covid-19, notably among those receiving high-flow oxygen or noninvasive ventilation.
Journal ArticleDOI
SARS-CoV-2 vaccine effectiveness against infection, symptomatic and severe COVID-19: a systematic review and meta-analysis
Paddy Ssentongo,Anna E. Ssentongo,Navya Voleti,Destin Groff,Ashley Sun,Djibril M. Ba,Jonathan J. Nunez,Leslie J. Parent,Vernon M. Chinchilli,Catharine I. Paules +9 more
TL;DR: A systematic review and meta-analysis of the duration of vaccine efficacy and effectiveness against SARS-CoV-2 infection, symptomatic, and severe COVID-19 was conducted in this article .
Journal ArticleDOI
Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phase 3 trial.
Andre C. Kalil,Aneesh K. Mehta,Thomas F Patterson,Nathaniel B. Erdmann,Carlos A. Gomez,Mamta K. Jain,Cameron R. Wolfe,Guillermo M. Ruiz-Palacios,Susan Kline,Justino Regalado Pineda,Anne F Luetkemeyer,Michelle Harkins,Patrick E. H. Jackson,Nicole M. Iovine,Victor F. Tapson,Myoung Don Oh,Jennifer A Whitaker,Richard A. Mularski,Catharine I. Paules,Dilek Ince,Jin Takasaki,Daniel A. Sweeney,Uriel Sandkovsky,David L. Wyles,Elizabeth L. Hohmann,Kevin Grimes,Robert Grossberg,Maryrose Laguio-Vila,Allison A Lambert,Diego Lopez de Castilla,Eu-Suk Kim,LuAnn Larson,Claire Ramsay Wan,Jessica Traenkner,Philip O Ponce,Jan E Patterson,Paul A. Goepfert,Theresa A. Sofarelli,Satish Mocherla,Emily R Ko,Alfredo Ponce de Leon,Sarah B Doernberg,Robert L. Atmar,Ryan C. Maves,Fernando Dangond,Jennifer Ferreira,Michelle Green,Mat Makowski,Tyler Bonnett,Tatiana Beresnev,Varduhi Ghazaryan,Walla Dempsey,Seema U Nayak,Lori E. Dodd,Kay M. Tomashek,John H. Beigel +55 more
TL;DR: In this article, the authors compared the efficacy of interferon beta-1a in combination with remdesivir in hospitalised patients with SARS-CoV-2 infection, as confirmed by a positive RT-PCR test, and the primary outcome was time to recovery, defined as the first day that a patient attained a category 1, 2, or 3 score on the eight-category ordinal scale.
Journal ArticleDOI
Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial
Cameron R. Wolfe,Kay M. Tomashek,Thomas L. Patterson,Carlos A. Gomez,Vincent C. Marconi,M. Jain,Otto O. Yang,Catharine I. Paules,Guillermo Miguel Ruiz Palacios,Robert Grossberg,Michelle Harkins,Richard A. Mularski,Nathaniel B. Erdmann,Uriel Sandkovsky,Eyad Almasri,Justino Regalado Pineda,Alexandra W. Dretler,Diego Lopez de Castilla,Angela Branche,Pauline K. Park,Aneesh K. Mehta,William R. Short,Susan McLellan,Susan Kline,Nicole M. Iovine,Hana M. El Sahly,Sarah B Doernberg,Myoung Don Oh,Nikhil Huprikar,Elizabeth L. Hohmann,Colleen F. Kelley,Mark Holodniy,Eu Suk Kim,Daniel A. Sweeney,Robert W. Finberg,Kevin A. Grimes,Ryan C. Maves,Emily R Ko,John J. Engemann,Barbara S. Taylor,Philip O Ponce,LuAnn Larson,Dante P. Melendez,Allan M. Seibert,Nadine Rouphael,Joslyn K. Strebe,Jesse L. Clark,Kathleen G. Julian,Alfredo Ponce de León,Anabela Cardoso,Stephanie de Bono,Robert L. Atmar,Anuradha Ganesan,Jennifer L. Ferreira,Michelle Green,Mat Makowski,Tyler Bonnett,Tatiana Beresnev,Varduhi Ghazaryan,Walla Dempsey,Seema U Nayak,Lori E. Dodd,John H. Beigel,Andre C. Kalil,L. Wahid,Emmanuel B. Walter,Akhila Belur,Grace Dreyer,Janet E. Patterson,Jason Bowling,D. O. Dixon,Angela L. Hewlett,Robert Odrobina,Jakrapun Pupaibool,S Mocherla,Suzana Lazarte,Meilani Cayabyab,Rezhan Hussein,Reshma Golamari,Kaleigh L. Krill,Sandra Rajme,Paul F. Riska,Barry S. Zingman,Gregory J. Mertz,Nestor Sosa,Paul A. Goepfert,Mezgebe Berhe,Emma Dishner,Mohamed Fayed,K. Hubel,José Arturo Martínez-Orozco,Nora Bautista Felix,Sammy T. Elmor,Amer Bechnak,Youssef Saklawi,Jason W. Van Winkle,Diego Fernando Zea,Maryrose Laguio-Vila,Edward E. Walsh,Ann R. Falsey,Karen L Carvajal,Robert C. Hyzy,Sinan Hanna,Norman Olbrich,Jessica Traenkner,Colleen S. Kraft,Pablo Tebas,Jillian Baron,Corri B. Levine,J. J. Nock,Joanne Billings,Hyun Kim,Marie-Carmelle Elie-Turenne,Jennifer A. Whitaker,Anne F Luetkemeyer,J. Dwyer,E. Bainbridge,Pyoeng Gyun Choe,Chang Kyung Kang,Nikolaus Jilg,Valeria D Cantos,Divya R. Bhamidipati,Srinivasa Nithin Gopalsamy,Aarthi Chary,Jongtak Jung,Kyoung Ho Song,Hong Bin Kim,Constance A. Benson,Kim McConnell,Jennifer P. Wang,Mireya Wessolossky,K.Y. Ayala Perez,Taryn A Eubank,Catherine M. Berjohn,Gregory Utz,Patrick E. H. Jackson,Taison D. Bell,Heather M. Haughey,Abeer Moanna,Sushma K. Cribbs,Telisha Harrison,C. Colombo,Christina Schofield,Rhonda E Colombo,Victor F. Tapson,Jonathan Grein,Fayyaz S. Sutterwala,Dilek Ince,Patricia L. Winokur,Monica Fung,Hannah Jang,David L. Wyles,Maria G. Frank,Ellen Sarcone,Henry Neumann,Anand Viswanathan,Sarah Hochman,Mark J. Mulligan,Benjamin J. Eckhardt,Ellie Carmody,Neera Ahuja,Kari C. Nadeau,David Svec,Jeffrey Macaraeg,Lee Alan Morrow,David Quimby,Mary T. Bessesen,Lindsay Nicholson,Jill C. Adams,Princy Kumar,Allison A. Lambert,Henry Arguinchona,Radica Z. Alicic,Sho Saito,Norio Ohmagari,Ayako Mikami,David Chien Lye,Tau Hong Lee,Po Ying Chia,Lanny Hsieh,Alpesh Amin,Miki Watanabe,Keith A. Candiotti,J. G. D. Castro,Maria A. Antor,Tida K. Lee,Tahaniyat Lalani,Richard M. Nowak,Andrea Wendrow,Scott Borgetti,Sarah L. George,Daniel F. Hoft,James D. Brien,Stuart H. Cohen,George Richard Thompson,Melony Chakrabarty,Faheem W. Guirgis,Richard T. Davey,Jocelyn Voell,Jeffrey R Strich,David A Lindholm,Katrin Mende,Trevor Wellington,Rekha R. Rapaka,Jennifer Husson,Andrea R. Levine,Seow Yen Tan,Huma Shafi,Jaime Chien,David C. Hostler,Jordanna Hostler,Brian Shahan,David Adams,Anu Osinusi,Huyen Cao,Timothy Burgess,Julia S. Rozman,Kevin K. Chung,C. Nieuwoudt,Jill El-Khorazaty,Heather Hill,Stephanie Pettibone,Nikki Gettinger,T. Engel,Teri Lewis,Jing Wang,Gregory Deye,Effie Y.H. Nomicos,Rhonda Pikaart-Tautges,Mohamed Elsafy,Robert Jurao,Hyung Chan Koo,Michael A. Proschan,Tammy Yokum,Janice Arega,Ruth H. Florese +235 more
TL;DR: The primary outcome was the difference in mechanical ventilation-free survival by day 29 between the two treatment groups in the modified intention-to-treat population.