C
Catherine M. Verfaillie
Researcher at Katholieke Universiteit Leuven
Publications - 576
Citations - 39157
Catherine M. Verfaillie is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Stem cell & Progenitor cell. The author has an hindex of 86, co-authored 548 publications receiving 36787 citations. Previous affiliations of Catherine M. Verfaillie include Veterans Health Administration & The Catholic University of America.
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Journal ArticleDOI
Pluripotency of mesenchymal stem cells derived from adult marrow
Yuehua Jiang,Balkrishna N. Jahagirdar,R. Lee Reinhardt,Robert E. Schwartz,C. Dirk Keene,Xilma R. Ortiz-Gonzalez,Morayma Reyes,Todd Lenvik,Troy C. Lund,Mark Blackstad,Jingbo Du,Sara Aldrich,Aaron Lisberg,Walter C. Low,David A. Largaespada,Catherine M. Verfaillie +15 more
TL;DR: It is reported here that cells co-purifying with mesenchymal stem cells—termed here multipotent adult progenitor cells or MAPCs—differentiate, at the single cell level, not only into meschymal cells, but also cells with visceral mesoderm, neuroectoderm and endoderm characteristics in vitro.
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Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation.
Robert H. Collins,Ofer Shpilberg,William R. Drobyski,D L Porter,Sergio Giralt,R Champlin,S A Goodman,S N Wolff,W Hu,Catherine M. Verfaillie,Alan F. List,William S. Dalton,N Ognoskie,Angela Chetrit,Joseph H. Antin,John Nemunaitis +15 more
TL;DR: DLI results in complete remissions in a high percentage of patients with relapsed chronic-phase CML, and acute and chronic GVHD post-DLI were highly correlated with disease response (P < .00001).
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Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells
TL;DR: MPCs that proliferate without obvious senescence under clinically applicable conditions and differentiate at the single-cell level not only into mesenchymal cells but also cells of visceral mesoderm may be an ideal source of stem cells for treatment of genetic or degenerative disorders affecting cells of mesodermal origin.
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Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells.
Robert E. Schwartz,Morayma Reyes,Lisa Koodie,Yuehua Jiang,Mark Blackstad,Troy C. Lund,Todd Lenvik,Sandra Johnson,Wei Shou Hu,Catherine M. Verfaillie +9 more
TL;DR: MAPCs, derived from normal human, mouse, and rat postnatal bone marrow primitive, multipotent adult progenitor cells, can differentiate into cells with morphological, phenotypic, and functional characteristics of hepatocytes, and may be an ideal cell for in vivo therapies for liver disorders or for use in bioartificial liver devices.
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Origin of endothelial progenitors in human postnatal bone marrow
Morayma Reyes,Arkadiusz Z. Dudek,Balkrishna N. Jahagirdar,Lisa Koodie,Paul H. Marker,Catherine M. Verfaillie +5 more
TL;DR: This study demonstrates that a CD34–, vascular endothelial cadherin–, VE-cadherin+, Flk1+ cells, and fetal liver kinase+ multipotent adult progenitor cell (MAPC) that copurifies with mesenchymal stem cells from postnatal human bone marrow is a progenitors for angioblasts.