C
Cathrine Hoyo
Researcher at North Carolina State University
Publications - 177
Citations - 8164
Cathrine Hoyo is an academic researcher from North Carolina State University. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 42, co-authored 151 publications receiving 6529 citations. Previous affiliations of Cathrine Hoyo include Duke University.
Papers
More filters
Journal ArticleDOI
450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy
Bonnie R. Joubert,Siri E. Håberg,Roy Miodini Nilsen,Xuting Wang,Stein Emil Vollset,Susan K. Murphy,Zhiqing Huang,Cathrine Hoyo,Øivind Midttun,Lea A. Cupul-Uicab,Per Magne Ueland,Michael C. Wu,Wenche Nystad,Douglas A. Bell,Shyamal D. Peddada,Stephanie J. London +15 more
TL;DR: The findings implicate epigenetic mechanisms in the pathogenesis of the adverse health outcomes associated with this important in utero exposure.
Journal ArticleDOI
DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
Bonnie R. Joubert,Janine F. Felix,Paul Yousefi,Kelly M. Bakulski,Allan C. Just,Carrie V. Breton,Sarah E. Reese,Christina A. Markunas,Christina A. Markunas,Rebecca C Richmond,Cheng-Jian Xu,Leanne K. Küpers,Sam S. Oh,Cathrine Hoyo,Olena Gruzieva,Cilla Söderhäll,Lucas A. Salas,Nour Baïz,Hongmei Zhang,Johanna Lepeule,Carlos Ruiz,Symen Ligthart,Tianyuan Wang,Jack A. Taylor,Liesbeth Duijts,Gemma C Sharp,Soesma A Jankipersadsing,Roy Miodini Nilsen,Ahmad Vaez,Ahmad Vaez,M. Daniele Fallin,Donglei Hu,Augusto A. Litonjua,Bernard F. Fuemmeler,Karen Huen,Juha Kere,Inger Kull,Monica Cheng Munthe-Kaas,Ulrike Gehring,Mariona Bustamante,Marie José Saurel-Coubizolles,Bilal M. Quraishi,Jie Ren,Jörg Tost,Juan R. González,Marjolein J. Peters,Siri E. Håberg,Zongli Xu,Joyce B. J. van Meurs,Tom R. Gaunt,Marjan Kerkhof,Eva Corpeleijn,Andrew P. Feinberg,Celeste Eng,Andrea A. Baccarelli,Sara E. Benjamin Neelon,Asa Bradman,Simon Kebede Merid,Anna Bergström,Zdenko Herceg,Hector Hernandez-Vargas,Bert Brunekreef,Mariona Pinart,Barbara Heude,Susan Ewart,Jin Yao,Nathanaël Lemonnier,Oscar H. Franco,Michael C. Wu,Albert Hofman,Albert Hofman,Wendy L. McArdle,Pieter van der Vlies,Fahimeh Falahi,Matthew W. Gillman,Lisa F. Barcellos,Ashok Kumar,Ashok Kumar,Ashok Kumar,Magnus Wickman,Magnus Wickman,Stefano Guerra,Marie-Aline Charles,John W. Holloway,Charles Auffray,Henning Tiemeier,George Davey Smith,Dirkje S. Postma,Marie-France Hivert,Brenda Eskenazi,Martine Vrijheid,Hasan Arshad,Josep M. Antó,Abbas Dehghan,Wilfried Karmaus,Isabella Annesi-Maesano,Jordi Sunyer,Akram Ghantous,Göran Pershagen,Nina Holland,Susan K. Murphy,Dawn L. DeMeo,Esteban G. Burchard,Christine Ladd-Acosta,Harold Snieder,Wenche Nystad,Gerard H. Koppelman,Caroline L Relton,Vincent W. V. Jaddoe,Allen J. Wilcox,Erik Melén,Erik Melén,Stephanie J. London +112 more
TL;DR: This large scale meta-analysis of methylation data identified numerous loci involved in response to maternal smoking in pregnancy with persistence into later childhood and provide insights into mechanisms underlying effects of this important exposure.
Journal ArticleDOI
Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort
Adelheid Soubry,Joellen M. Schildkraut,Amy P. Murtha,Frances Wang,Zhiqing Huang,Autumn J. Bernal,Joanne Kurtzberg,Randy L. Jirtle,Susan K. Murphy,Cathrine Hoyo +9 more
TL;DR: The data indicate a preconceptional impact of paternal obesity on the reprogramming of imprint marks during spermatogenesis and suggest an increase in DNA methylation at the IGF2 and H19 DMRs among newborns from obese mothers, but a larger study is warranted to further explore the potential effects of maternal obesity or lifestyle on the offspring's epigenome.
Journal ArticleDOI
Newborns of obese parents have altered DNA methylation patterns at imprinted genes.
Adelheid Soubry,Susan K. Murphy,Frances Wang,Zhiqing Huang,Adriana C. Vidal,Bernard F. Fuemmeler,Joanne Kurtzberg,Amy P. Murtha,Randy L. Jirtle,Joellen M. Schildkraut,Cathrine Hoyo +10 more
TL;DR: A significant and independent association between paternal obesity and the offspring’s methylation status suggests the susceptibility of the developing sperm for environmental insults and altered methylation outcomes at multiple imprint regulatory regions in children born to obese parents, compared with childrenBorn to non-obese parents.
Journal ArticleDOI
A paternal environmental legacy: Evidence for epigenetic inheritance through the male germ line
TL;DR: This essay suggests the existence of epigenetic windows of susceptibility to environmental insults during sperm development and suggests changes in DNA methylation, histone modification, and non‐coding RNAs are viable mechanistic candidates for a non‐genetic transfer of paternal environmental information, from maturing germ cell to zygote.