C
Catriona Jamieson
Researcher at University of California, San Diego
Publications - 238
Citations - 15384
Catriona Jamieson is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Stem cell & Progenitor cell. The author has an hindex of 46, co-authored 210 publications receiving 13755 citations. Previous affiliations of Catriona Jamieson include University of Toronto & Mayo Clinic.
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Journal ArticleDOI
Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells.
Michael F. Clarke,John E. Dick,Peter B. Dirks,Connie J. Eaves,Catriona Jamieson,D. Leanne Jones,Jane E. Visvader,Irving L. Weissman,Geoffrey M. Wahl +8 more
TL;DR: A workshop was convened by the AACR to discuss the rapidly emerging cancer stem cell model for tumor development and progression, and participants were charged with evaluating data suggesting that cancers develop from a small subset of cells with self-renewal properties analogous to organ regeneration.
Journal ArticleDOI
Granulocyte-Macrophage Progenitors as Candidate Leukemic Stem Cells in Blast-Crisis CML
Catriona Jamieson,Laurie Ailles,Scott J. Dylla,Manja Muijtjens,Carol D. Jones,James L. Zehnder,Jason Gotlib,Kevin Li,Markus G. Manz,Armand Keating,Charles L. Sawyers,Irving L. Weissman +11 more
TL;DR: Activation of beta-catenin in CML granulocyte-macrophage progenitors appears to enhance the self-renewal activity and leukemic potential of these cells.
Journal ArticleDOI
CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis
Siddhartha Jaiswal,Catriona Jamieson,Wendy W. Pang,Christopher Y. Park,Mark P. Chao,Ravindra Majeti,David Traver,Nico van Rooijen,Irving L. Weissman +8 more
TL;DR: It is concluded that CD47 upregulation is an important mechanism that provides protection to normal HSCs during inflammation-mediated mobilization, and that leukemic progenitors co-opt this ability in order to evade macrophage killing.
Journal ArticleDOI
Stems cells and the pathways to aging and cancer.
TL;DR: Evidence linking stem cell dysfunction to the pathophysiological conditions accompanying aging is examined, focusing on the mechanisms underlying stem cell decline and their contribution to disease pathogenesis.
Journal ArticleDOI
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
Chen Zhao,Alan Chen,Catriona Jamieson,Mark Fereshteh,Annelie Abrahamsson,Jordan M. Blum,Hyog Young Kwon,Jynho Kim,John P. Chute,David A. Rizzieri,Michael John Munchhof,Todd VanArsdale,Philip A. Beachy,Tannishtha Reya +13 more
TL;DR: It is shown that the loss of Smoothened (Smo), an essential component of the Hh pathway, impairs haematopoietic stem cell renewal and decreases induction of chronic myelogenous leukaemia (CML) by the BCR–ABL1 oncoprotein.