C
Cecilia G. Sanchez
Researcher at Tulane University
Publications - 26
Citations - 1666
Cecilia G. Sanchez is an academic researcher from Tulane University. The author has contributed to research in topics: Pulmonary fibrosis & Idiopathic pulmonary fibrosis. The author has an hindex of 17, co-authored 26 publications receiving 1497 citations. Previous affiliations of Cecilia G. Sanchez include University of Arizona & Pasteur Institute.
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Journal ArticleDOI
ICF, An Immunodeficiency Syndrome: DNA Methyltransferase 3B Involvement, Chromosome Anomalies, and Gene Dysregulation
Melanie Ehrlich,Cecilia G. Sanchez,Chunbo Shao,Rie Nishiyama,John H. Kehrl,Rork Kuick,Takeo Kubota,Samir M. Hanash +7 more
TL;DR: It is proposed that hypomethylation of satellite 2 at 1qh and 16qh might provoke this dysregulation gene expression by trans effects from altered sequestration of transcription factors, changes in nuclear architecture, or expression of noncoding RNAs.
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Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1
Meredith L. Sosulski,Rafael Gongora,Svitlana Danchuk,Chunmin Dong,Fayong Luo,Cecilia G. Sanchez +5 more
TL;DR: This study indicates that an age‐related decline in autophagy and mitophagy responses to lung injury may contribute to the promotion and/or perpetuation of pulmonary fibrosis and proposes that promotion of autophagic and mitochondrial quality control may offer an intervention against age-related fibrotic diseases.
Conserved Interaction Between Distinct Krüppel-associated box Domains and the Transcriptional Intermediary factor 1β
Magnus Åbrink,José A. Ortiz,Charlotta Mark,Cecilia G. Sanchez,Camilla Looman,Lars Hellman,Pierre Chambon,Régine Losson +7 more
TL;DR: Taken together, these results implicate TIF1 beta as a common transcriptional corepressor for the three distinct subfamilies of KRAB zinc-finger proteins and suggest a high degree of conservation in the molecular mechanism underlying their transcriptional repression activity.
Journal ArticleDOI
Activation of autophagy in mesenchymal stem cells provides tumor stromal support.
Cecilia G. Sanchez,Patrice Penfornis,Adam Z. Oskowitz,Aaron G. Boonjindasup,David Z. Cai,Santosh S. Dhule,Brian G. Rowan,Ameeta Kelekar,Diane S. Krause,Radhika Pochampally +9 more
TL;DR: In vitro studies demonstrate that SD-MSCs survive using autophagy and secrete paracrine factors that support tumor cells following nutrient/serum deprivation, and suggest that under nutrient-deprived conditions that can occur in solid tumors, stromal cells utilize autophile for survival and also secrete anti-apoptotic factors that can facilitate solid tumor survival and growth.