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Ch Marazano

Bio: Ch Marazano is an academic researcher from Kōchi University. The author has contributed to research in topics: Limonin & Aphanamixis. The author has an hindex of 1, co-authored 1 publications receiving 43 citations. Previous affiliations of Ch Marazano include Arizona State University & Institut de Chimie des Substances Naturelles.

Papers
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Journal ArticleDOI
TL;DR: 2 new limonoid-type terpenes have been isolated from an aqueous extract of seeds produced by the Eastern Himalayan (India) plant by interpreting principally mass spectral and nuclear magnetic resonance data.
Abstract: 2 new limonoid-type terpenes have been isolated from an aqueous extract of seeds produced by the Eastern Himalayan (India) plant Aphanamixis grandifolia B1. By interpreting principally mass spectral and nuclear magnetic resonance data, the structures of 12-hydroxyamoorastatin (2b) and amoorastatone (3) were elucidated. Unequivocal evidence for the 12-hydroxyamoorastatin structural assignment was obtained by chemical conversion to sendanin (4). Amoorastatin derivative 2b was found to significantly inhibit growth of the murine P388 lymphocytic leukemia cell lines but amoorastatone in the same system was inactive. In a comparative biological study, sendanin (4) and anthothecol (7) were also found significantly to inhibit growth of the P388 cell line, while rohitukin (8) and limonin (9) were found to be inactive.

44 citations


Cited by
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Journal ArticleDOI
TL;DR: This review summarizes the literature on the biological activities of limonoid of known structure, and attempts to relate those activities to current concepts of the evolution of the limonoids.

407 citations

Journal ArticleDOI
TL;DR: This paper aims to demonstrate the efforts towards in-situ applicability of EMMARM, as to provide real-time information about concrete mechanical properties such as E-modulus and compressive strength.
Abstract: Natural Science Foundation of China[30000213, 30370160, 30670214]; National Basic Research Program of China (973 Program)[2009CB522300]; Chinese Academy of Sciences

372 citations

Journal ArticleDOI
TL;DR: Four new tetranortriterpenes, meliatoxins A1, A2, B1 and B2 have been isolated and identified as toxic constituents of the fruit of Melia azedarach L. var.

89 citations

Journal ArticleDOI
TL;DR: Systematic fractionation of a fruit extract from Argentine Melia azedarach L., which was monitored by an insect antifeedant bioassay, led to the isolation of meliartenin, a limonoid antifeingant, which existed as a mixture of two interchangeable isomers.
Abstract: Systematic fractionation of a fruit extract from Argentine Melia azedarach L., which was monitored by an insect antifeedant bioassay, led to the isolation of meliartenin, a limonoid antifeedant, which existed as a mixture of two interchangeable isomers. At 4 μg/cm2 and 1 μg/cm2, the isomeric mixture was as active as azadirachtin in strongly inhibiting the larval feeding of Epilachna paenulata Germ. (Coleoptera: Coccinellidae) and the polyphagous pest, Spodoptera eridania (Lepidoptera: Noctuidae), respectively.

84 citations

Book ChapterDOI
01 Jan 1984
TL;DR: The chemistry of the limonoids was reviewed in this series by Dreyer (84); a more recent review is by Connolly, Overton and Polonsky (73), and taxonomic aspects have been reviewed recently by the present author.
Abstract: The purpose of this article is to review the chemistry of the limonoids isolated from plants of the natural order Meliaceae; limonoids from the Rutaceae and Cneoraceae are not included. The chemistry of the limonoids was last reviewed in this series by Dreyer (84); a more recent review is by Connolly, Overton and Polonsky (73). Taxonomic aspects have been reviewed recently by the present author (199), and chemistry and phyto-chemistry have been discussed at a recent meeting (81). The present article sets out to review advances in limonoid chemistry since the last review in this series (84); the tables however are intended to be comprehensive.

59 citations