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Chad E. Eckert

Bio: Chad E. Eckert is an academic researcher from Ethicon Inc.. The author has contributed to research in topics: Surgical instrument & Ventricular assist device. The author has an hindex of 15, co-authored 45 publications receiving 1101 citations. Previous affiliations of Chad E. Eckert include University of Pittsburgh & Johnson & Johnson.

Papers
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Patent
10 Aug 2016
TL;DR: In this article, a staple assembly including staples is described, which includes features which improve the biocompatibility and/or bioabsorption of the staples, such as magnesium alloy, zinc, and metal-oxide.
Abstract: A staple cartridge assembly including staples is disclosed herein. The staples comprise features which improve the biocompatibility and/or bioabsorption of the staples. The staples are comprised of a magnesium alloy, for example. The magnesium alloy can also include zinc. In certain instances, a bioabsorbable polymer is coated on part of, but not all of, the staple. Portions of the staple that are not coated by the bioabsorbable polymer will be absorbed at a first rate while portions of the staple that are coated by the bioabsorbable polymer will be absorbed at a slower rate. In various instances, the tips of the magnesium staples are coated with magnesium nitride and/or any other suitable material which can increase the hardness of the staples. In certain instances, the staples are coated in silver. In some instances, the staples include one or more apertures defined therein.

328 citations

Patent
31 Aug 2015
TL;DR: In this article, an implantable adjunct can be configured to be applied to tissue by a surgical stapler in conjunction with staples, and one or more medicants releasably retained therein that are effective to provide a desired effect on tissue in-growth in a predetermined manner.
Abstract: Adjunct material to promote tissue growth is provided. In general, an implantable adjunct can be configured to be applied to tissue by a surgical stapler in conjunction with staples. The adjunct can have one or more medicants releasably retained therein that are effective to provide a desired effect on tissue in-growth in a predetermined manner. One or more characteristics associated with the adjunct can be altered between various implementations to promote organized tissue remodeling in a desired manner during wound healing, such as by encouraging tissue growth to be in a certain direction and/or by discouraging tissue growth in a certain area and/or on a certain structure.

148 citations

Journal ArticleDOI
TL;DR: The results suggest that surgically introduced alterations in MV shape could lead to the long term MV mechanobiological and microstructural alterations that could ultimately affect MV repair durability.
Abstract: Alteration of the native mitral valve (MV) shape has been hypothesized to have a profound effect on the local tissue stress distribution, and is potentially linked to limitations in repair durability. The present study was undertaken to elucidate the relation between MV annular shape and central mitral valve anterior leaflet (MVAL) strain history, using flat annuloplasty in an ovine model. In addition, we report for the first time the presence of residual in vivo leaflet strains. In vivo leaflet deformations were measured using sonocrystal transducers sutured to the MVAL (n = 10), with the 3D positions acquired over the full cardiac cycle. In six animals a flat ring was sutured to the annulus and the transducer positions recorded, while in the remaining four the MV was excised from the exsanguinated heart and the stress-free transducer positions obtained. In the central region of the MVAL the peak stretch values, referenced to the minimum left ventricular pressure (LVP), were 1.10 ± 0.01 and 1.31 ± 0.03 (mean ± standard error) in the circumferential and radial directions, respectively. Following flat ring annuloplasty, the central MVAL contracted 28% circumferentially and elongated 16% radially at minimum LVP, and the circumferential direction was under a negative strain state during the entire cardiac cycle. After valve excision from the exsanguinated heart, the MVAL contracted significantly (18 and 30% in the circumferential and radial directions, respectively), indicating the presence of substantial in vivo residual strains. While the physiological function of the residual strains (and their associated stresses) are at present unknown, accounting for their presence is clearly necessary for accurate computational simulations of MV function. Moreover, we demonstrated that changes in annular geometry dramatically alter valvular functional strains in vivo. As levels of homeostatic strains are related to tissue remodeling and homeostasis, our results suggest that surgically introduced alterations in MV shape could lead to the long term MV mechanobiological and microstructural alterations that could ultimately affect MV repair durability.

93 citations

Journal ArticleDOI
TL;DR: Blood pressure control can be achieved in patients with CF LVADs, with the majority of patients requiring only 1 or 2 antihypertensives, according to a predefined institutional protocol.

86 citations

Journal ArticleDOI
TL;DR: Analysis of Interagency Registry for Mechanically Assisted Circulatory Support data showed greater durability for continuous flow than for pulsatile left ventricular assist devices.

71 citations


Cited by
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Patent
14 Jun 2016
TL;DR: Newness and distinctiveness is claimed in the features of ornamentation as shown inside the broken line circle in the accompanying representation as discussed by the authors, which is the basis for the representation presented in this paper.
Abstract: Newness and distinctiveness is claimed in the features of ornamentation as shown inside the broken line circle in the accompanying representation.

1,500 citations

Patent
20 Sep 2016
TL;DR: In this article, an E-beam firing bar is used to drive staples on each side of the cut in a surgical severing and stapling instrument, which is suitable for laparoscopic and endoscopic clinical procedures, clamps tissue within an end effector of an elongate channel pivotally opposed by an anvil.
Abstract: A surgical severing and stapling instrument, suitable for laparoscopic and endoscopic clinical procedures, clamps tissue within an end effector of an elongate channel pivotally opposed by an anvil. An E-beam firing bar moves distally through the clamped end effector to sever tissue and to drive staples on each side of the cut. The E-beam firing bar affirmatively spaces the anvil from the elongate channel to assure properly formed closed staples, especially when an amount of tissue is clamped that is inadequate to space the end effector. In particular, an upper pin of the firing bar longitudinally moves through an anvil slot and a channel slot is captured between a lower cap and a middle pin of the firing bar to assure a minimum spacing. Forming the E-beam from a thickened distal portion and a thinned proximal strip enhances manufacturability and facilitates use in such articulating surgical instruments.

1,384 citations

Patent
24 May 2016
TL;DR: In this paper, a surgical stapler having a staple cartridge, an anvil, a cutting member having a cutting surface, and a driver operably engaged with the cutting member to move the member relative to the anvil and the staple cartridge is presented.
Abstract: The present invention includes a surgical stapler having a staple cartridge, an anvil, a cutting member having a cutting surface, and a driver operably engaged with the cutting member to move the cutting member relative to the anvil and the staple cartridge. In at least one embodiment, one of the anvil and the staple cartridge defines a slot which is configured to receive at least a portion of the cutting member and guide the cutting member as it is moved relative to the anvil and the staple cartridge. In these embodiments, the slot can also be configured to receive a portion of the driver operably engaged with cutting member and support the driver when it moves the cutting member. In at least one embodiment, the slot is defined by at least one radius of curvature.

932 citations

Patent
07 Apr 2016
TL;DR: In this article, an end effector is coupled to a rotary actuation motion and rotary retraction motion from a robotic system that is configured to generate the rotary actuator motion and said rotary retractor motion.
Abstract: A surgical instrument including an end effector that has a selectively reciprocatable implement movably supported therein. The implement is selectively advanceable in a distal direction upon application of a rotary actuation motion thereto and retractable in a proximal direction upon application of a rotary retraction motion thereto. An elongate shaft assembly is coupled to the end effector and is configured to transmit the rotary actuation motion and rotary retraction motion to the reciprocatable implement from a robotic system that is configured to generate the rotary actuation motion and said rotary retraction motion.

825 citations

Patent
22 Aug 2014
TL;DR: Surgical end effectors and fastener cartridges having firing lockout arrangements for preventing or limiting a firing stroke when a cartridge has not been operably installed in the end effector or a spent cartridge has been replaced as mentioned in this paper.
Abstract: Surgical end effectors and fastener cartridges having firing lockout arrangements for preventing or limit a firing stroke when a cartridge has not been operably installed in the end effector or a spent cartridge has not been replaced.

781 citations