C
Chao Xu
Researcher at Chinese Academy of Sciences
Publications - 999
Citations - 28763
Chao Xu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Computer science & Medicine. The author has an hindex of 75, co-authored 845 publications receiving 20541 citations. Previous affiliations of Chao Xu include Structural Genomics Consortium & Harbin Institute of Technology.
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Journal ArticleDOI
Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA, Cytoscape and EnrichmentMap
Jüri Reimand,Jüri Reimand,Ruth Isserlin,Veronique Voisin,Mike Kucera,Christian Tannus-Lopes,Asha Rostamianfar,Lina Wadi,Mona Meyer,Judy M. Y. Wong,Chao Xu,Daniele Merico,Gary D. Bader +12 more
TL;DR: This protocol describes pathway enrichment analysis of gene lists from RNA-seq and other genomics experiments using g:Profiler, GSEA, Cytoscape and EnrichmentMap software, and describes innovative visualization techniques.
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Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain
Chao Xu,Xiao Wang,Ke Liu,Ian A Roundtree,Wolfram Tempel,Yanjun Li,Zhike Lu,Chuan He,Chuan He,Jinrong Min +9 more
TL;DR: These structural studies, together with transcriptome-wide identification of YTHDC1-binding sites and biochemical experiments, not only reveal the specific mode of m(6)A-YTH binding but also explain the preferential recognition of the GG(m( 6)A)C)C sequences by YTH DC1.
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Structure and function of WD40 domain proteins.
Chao Xu,Jinrong Min +1 more
TL;DR: The identification, definition and architecture of the WD40 domains are discussed, and how post-translational modifications are recognized by the large versatile family of WD40 domain proteins are discussed.
Journal ArticleDOI
Improved Performance of the Silicon Anode for Li-Ion Batteries: Understanding the Surface Modification Mechanism of Fluoroethylene Carbonate as an Effective Electrolyte Additive
Chao Xu,Fredrik Lindgren,Bertrand Philippe,Mihaela Gorgoi,Fredrik Björefors,Kristina Edström,Torbjörn Gustafsson +6 more
TL;DR: In this article, fluoroethylene carbonate (FEC) was used as an electrolyte additive, which significantly improved the cyclability of silicon-based electrodes and suppressed further salt degradation.
Journal ArticleDOI
Identifying the Recognition Site for Selective Trapping of 99TcO4– in a Hydrolytically Stable and Radiation Resistant Cationic Metal–Organic Framework
Lin Zhu,Daopeng Sheng,Chao Xu,Xing Dai,Mark A. Silver,Jie Li,Peng Li,Yaxing Wang,Yanlong Wang,Lanhua Chen,Chengliang Xiao,Jing Chen,Ruhong Zhou,Chao Zhang,Omar K. Farha,Omar K. Farha,Zhifang Chai,Thomas E. Albrecht-Schmitt,Shuao Wang +18 more
TL;DR: A hydrolytically stable and radiation-resistant cationic metal-organic framework (MOF), SCU-101, exhibiting extremely fast removal kinetics, exceptional distribution coefficient, and high sorption capacity toward TcO4 is reported, capable of effectively separating T cO4- from Hanford low-level waste melter off-gas scrubber simulant stream.