Author
Chia-Hung Kuo
Other affiliations: National Taiwan University, Wuyi University, National Chung Hsing University ...read more
Bio: Chia-Hung Kuo is an academic researcher from National Kaohsiung Marine University. The author has contributed to research in topics: Lipase & Cellulase. The author has an hindex of 22, co-authored 67 publications receiving 1572 citations. Previous affiliations of Chia-Hung Kuo include National Taiwan University & Wuyi University.
Topics: Lipase, Cellulase, Response surface methodology, Fucoidan, Cellulose
Papers published on a yearly basis
Papers
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TL;DR: In this article, four cellulose dissolution agents, NaOH/Urea solution, N-methylmorpholine-Noxide (NMMO), ionic liquid (1-butyl-3methylimidazolium chloride; [BMIM]Cl) and 85% phosphoric acid were employed to dissolve cotton cellulose.
269 citations
TL;DR: In this article, the authors used magnetic Fe 3 O 4 -chitosan nanoparticles for the covalent immobilization of lipase from Candida rugosa using N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) and N-hydroxysuccinimides (NHS) as coupling agents.
188 citations
TL;DR: The cellulose dissolution solvent used in Lyocell process for cellulose fiber preparation, N-methylmorpholine-N-oxide (NMMO) monohydrate, was demonstrated to be an effective agent for sugarcane bagasse pretreatment and exhibited a significant enhancement on enzymatic hydrolysis kinetic.
164 citations
TL;DR: It is demonstrated that acetate buffered medium can effectively improve BC pellicle production in a static cultivation by maintaining a pH suitable for BC production during static cultivation.
79 citations
TL;DR: In this article, a targeted piceid was encapsulated into a liposomal formula as aqueous substrate to overcome its poor water-solubility, which could cause a coupled problem of biological activities concerning drug dispersion and absorption in human body, which is still unsolved now.
57 citations
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TL;DR: In this article, a comprehensive state of the art describing the advancement in recent pretreaments, metabolic engineering approaches with special emphasis on the latest developments in consolidated biomass processing, current global scenario of bioethanol pilot plants and biorefinery concept for the production of biofuels and bioproducts.
1,369 citations
TL;DR: In this article, the application of ionic liquids to the deconstruction and fractionation of lignocellulosic biomass, in a process step that is commonly called pretreatment, is discussed.
1,260 citations
TL;DR: Ionic liquid pretreatment enabled a significant enhancement in the rate of enzyme hydrolysis of the cellulose component of switchgrass, with a rate increase of 16.7-fold, and a glucan yield of 96.0% obtained in 24h.
995 citations
TL;DR: An extensive research is still required for the development of new and more efficient pretreatment processes for lignocellulosic feedstocks yielding promising results.
Abstract: Lignocellulosic feedstock materials are the most abundant renewable bioresource material available on earth. It is primarily composed of cellulose, hemicellulose, and lignin, which are strongly associated with each other. Pretreatment processes are mainly involved in effective separation of these complex interlinked fractions and increase the accessibility of each individual component, thereby becoming an essential step in a broad range of applications particularly for biomass valorization. However, a major hurdle is the removal of sturdy and rugged lignin component which is highly resistant to solubilization and is also a major inhibitor for hydrolysis of cellulose and hemicellulose. Moreover, other factors such as lignin content, crystalline, and rigid nature of cellulose, production of post-pretreatment inhibitory products and size of feed stock particle limit the digestibility of lignocellulosic biomass. This has led to extensive research in the development of various pretreatment processes. The major pretreatment methods include physical, chemical, and biological approaches. The selection of pretreatment process depends exclusively on the application. As compared to the conventional single pretreatment process, integrated processes combining two or more pretreatment techniques is beneficial in reducing the number of process operational steps besides minimizing the production of undesirable inhibitors. However, an extensive research is still required for the development of new and more efficient pretreatment processes for lignocellulosic feedstocks yielding promising results.
908 citations
TL;DR: Different leading pretreatment technologies are reviewed along with their latest developments and their advantages and disadvantages with respect to subsequent hydrolysis and fermentation with a focus on how the treatment greatly enhances enzymatic cellulose digestibility.
Abstract: Overcoming the recalcitrance (resistance of plant cell walls to deconstruction) of lignocellulosic biomass is a key step in the production of fuels and chemicals. The recalcitrance is due to the highly crystalline structure of cellulose which is embedded in a matrix of polymers-lignin and hemicellulose. The main goal of pretreatment is to overcome this recalcitrance, to separate the cellulose from the matrix polymers, and to make it more accessible for enzymatic hydrolysis. Reports have shown that pretreatment can improve sugar yields to higher than 90% theoretical yield for biomass such as wood, grasses, and corn. This paper reviews different leading pretreatment technologies along with their latest developments and highlights their advantages and disadvantages with respect to subsequent hydrolysis and fermentation. The effects of different technologies on the components of biomass (cellulose, hemicellulose, and lignin) are also reviewed with a focus on how the treatment greatly enhances enzymatic cellulose digestibility.
810 citations