C
Chiranjib Pal
Researcher at West Bengal State University
Publications - 49
Citations - 897
Chiranjib Pal is an academic researcher from West Bengal State University. The author has contributed to research in topics: Leishmania donovani & Medicine. The author has an hindex of 14, co-authored 42 publications receiving 747 citations. Previous affiliations of Chiranjib Pal include Indian Institute of Chemical Biology & Brahmananda Keshab Chandra College.
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Journal ArticleDOI
Luteolin, an abundant dietary component is a potent anti-leishmanial agent that acts by inducing topoisomerase II-mediated kinetoplast DNA cleavage leading to apoptosis.
Bidyottam Mittra,Asim Saha,Arnab Roy Chowdhury,Chiranjib Pal,Suparna Mandal,Sibabrata Mukhopadhyay,Santu Bandyopadhyay,Hemanta K. Majumder +7 more
TL;DR: Luteolin has great promise for acting as a lead compound in the chemotherapy of leishmaniasis, a major concern in developing countries, and can be a strong candidate for antileishmanial drug design.
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Synthesis of a Novel Quinoline Derivative, 2-(2-Methylquinolin-4- ylamino)-N-phenylacetamide—A Potential Antileishmanial Agent
Niranjan P. Sahu,Chiranjib Pal,Nirup B. Mandal,Sukdeb Banerjee,Mausumi Raha,Ashis P. Kundu,Anirban Basu,Monidipa Ghosh,Keshab Chandra Roy,Santu Bandyopadhyay +9 more
TL;DR: 2-(2-Methylquinolin-4-ylamino)-N-phenylacetamide (2) was found to be significantly more active than the standard antileishmanial drug sodium antimony gluconate (SAG) in reducing the parasite load both in the spleen and liver at a much lower concentration in hamster models.
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Dendritic cell-based immunotherapy combined with antimony-based chemotherapy cures established murine visceral leishmaniasis.
TL;DR: Data indicate that DC-based immunotherapy enhances the in vivo antileishmanial potential of antimony or vice versa, andetitive in vitro stimulation of splenocytes from uninfected or L. donovani-infected mice with SLDA-pulsed DCs led to the emergence of CD4+ T cells with characteristics of Th1 cells.
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Leishmanicidal and Anticandidal Activity of Constituents of Indian Edible Mushroom Astraeus hygrometricus
Tapan K. Lai,Gunjan Biswas,Soumya Chatterjee,Aritri Dutta,Chiranjib Pal,Julie Banerji,Nattamai Bhuvanesh,Joseph H. Reibenspies,Krishnendu Acharya +8 more
TL;DR: Two new lanostane‐type triterpenes, 1 and 2, were isolated from Astraeus hygrometricus and exhibited excellent in vitro toxicities against Candida albicans, comparable to standard antifungal antibiotics.
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Selective inhibition of Leishmania donovani by active extracts of wild mushrooms used by the tribal population of India: An in vitro exploration for new leads against parasitic protozoans.
Suvadip Mallick,Aritri Dutta,Somaditya Dey,Joydip Ghosh,Debarati Mukherjee,Sirin Salma Sultana,Supratim Mandal,Soumitra Paloi,Somanjana Khatua,Krishnendu Acharya,Chiranjib Pal +10 more
TL;DR: Results of this study can be used as a basis for further phytochemical and pharmacological investigations in the effort for search of novel anti-leishmanial leads.