C
Chris Sander
Researcher at Harvard University
Publications - 730
Citations - 273726
Chris Sander is an academic researcher from Harvard University. The author has contributed to research in topics: Large Hadron Collider & Protein structure. The author has an hindex of 178, co-authored 713 publications receiving 233287 citations. Previous affiliations of Chris Sander include Purdue University & University of Leeds.
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How good are predictions of protein secondary structure
Wolfgang Kabsch,Chris Sander +1 more
TL;DR: The three most widely used methods for the prediction of protein secondary structure from the amino acid sequence are tested on 62 proteins of known structure using a program package and data collection not previously available.
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Mitochondrial DNA copy number variation across human cancers
Ed Reznik,Martin L. Miller,Yasin Senbabaoglu,Nadeem Riaz,Judy Sarungbam,Satish K. Tickoo,Hikmat Al-Ahmadie,William Lee,Venkatraman E. Seshan,A. Ari Hakimi,Chris Sander +10 more
TL;DR: It is found that some tumors may compensate for mtDNA depletion to sustain levels of respiratory proteins, and point to related therapeutic opportunities.
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Automated network analysis identifies core pathways in glioblastoma.
TL;DR: It is confirmed and extended the observation that GBM alterations tend to occur within specific functional modules, in spite of considerable patient-to-patient variation, and that two of the largest modules involve signaling via p53, Rb, PI3K and receptor protein kinases.
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Completeness in structural genomics.
TL;DR: This work evaluates different strategies for optimizing information return on effort and concludes that the strategy that maximizes structural coverage requires about seven times fewer structure determinations compared with the strategy in which targets are selected at random.
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The primary structure of transcription factor TFIIIA has 12 consecutive repeats
TL;DR: Analysis of the amino acid sequence of transcription factor TFIIIA from Xenopuslaevis reveals the presence of 12 repeating structures, each about 30 residues in length, which may be used to coordinate a zinc cation.