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Chris Sander

Researcher at Harvard University

Publications -  730
Citations -  273726

Chris Sander is an academic researcher from Harvard University. The author has contributed to research in topics: Large Hadron Collider & Protein structure. The author has an hindex of 178, co-authored 713 publications receiving 233287 citations. Previous affiliations of Chris Sander include Purdue University & University of Leeds.

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Detection of common three-dimensional substructures in proteins

Gerrit Vriend, +1 more
- 01 Sep 1991 - 
TL;DR: A fully automatic algorithm for three‐dimensional alignment of protein structures and for the detection of common substructures and structural repeats is presented, so fast that structural comparison of a single protein with the entire database of known protein structures can be performed routinely on a workstation.
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Automated genome sequence analysis and annotation.

Miguel A. Andrade, +10 more
- 01 May 1999 - 
TL;DR: An automatic system for preliminary functional annotation of protein sequences that has been applied to the analysis of sets of sequences from complete genomes, both to refine overall performance and to make new discoveries comparable to those made by human experts is presented.
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Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma.

Samuel Singer, +11 more
- 15 Jul 2007 - 
TL;DR: It is shown that Nutlin-3a, an antagonist of MDM2, preferentially induces apoptosis and growth arrest in dedifferentiated liposarcoma cells compared with normal adipocytes, and the promise of using this expression dataset for new drug discovery in liposARcoma is shown.
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Performance of missing transverse momentum reconstruction with the ATLAS detector using proton-proton collisions at s√ = 13 TeV

Morad Aaboud, +2881 more
- 08 Nov 2018 - 
TL;DR: The performance of the missing transverse momentum reconstruction with the ATLAS detector is evaluated using data collected in proton–proton collisions at the LHC at a centre-of-mass energy of 13 TeV in 2015.
DOI

FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation

Caroline Junqueira, +31 more
TL;DR: It is suggested that antibody-mediated SARS-CoV-2 uptake by monocytes/macrophages triggers inflammatory cell death that aborts production of infectious virus but causes systemic inflammation that contributes to COVID-19 pathogenesis.