C
Christian Doerig
Researcher at RMIT University
Publications - 168
Citations - 10687
Christian Doerig is an academic researcher from RMIT University. The author has contributed to research in topics: Plasmodium falciparum & Kinase. The author has an hindex of 55, co-authored 155 publications receiving 9621 citations. Previous affiliations of Christian Doerig include French Institute of Health and Medical Research & Anderson University (Indiana).
Papers
More filters
Journal ArticleDOI
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
Simon D. Harding,Joanna L. Sharman,Elena Faccenda,Christopher Southan,Adam J. Pawson,Sam M. Ireland,Alasdair J. G. Gray,Liam Bruce,Stephen P.H. Alexander,Stephen M. Anderton,Clare E. Bryant,Anthony P. Davenport,Christian Doerig,Doriano Fabbro,Francesca Levi-Schaffer,Michael Spedding,Jamie A. Davies,Nc-Iuphar +17 more
TL;DR: This update describes content expansion, new features and interoperability improvements introduced in the 10 releases since August 2015, and introduces the newly funded project for the Guide to IMMUNOPHARMACOLOGY (GtoImmuPdb, www.guidetoimmunopharmacology.org).
Journal ArticleDOI
Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote
TL;DR: An exhaustive analysis of the P. falciparum genomic database (PlasmoDB) aimed at identifying and classifying all ePKs in this organism found that profound divergences between the kinome of malaria parasites and that of yeast or mammalian cells are reflected.
Journal ArticleDOI
Two-dimensional single-cell patterning with one cell per well driven by surface acoustic waves
David J. Collins,Belinda Joan Morahan,Jose F. Garcia-Bustos,Christian Doerig,Magdalena Plebanski,Adrian Neild +5 more
TL;DR: A new method for the patterning of multiple spatially separated single particles and cells using high-frequency acoustic fields with one cell per acoustic well is introduced, made possible by a hitherto unexplored regime where the acoustic wavelength is on the same order as the cell dimensions.
Journal ArticleDOI
Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum
Lev Solyakov,Jean Halbert,Jean Halbert,Mahmood M. Alam,Jean-Phillipe Semblat,Jean-Phillipe Semblat,Dominique Dorin-Semblat,Dominique Dorin-Semblat,Luc Reininger,Luc Reininger,Andrew R. Bottrill,Sharad Mistry,Abdirhaman Abdi,Abdirhaman Abdi,Clare Fennell,Zoe Holland,Claudia Demarta,Yvan Bouza,Audrey Sicard,Audrey Sicard,Marie-Paule Nivez,Sylvain C.P. Eschenlauer,Tenzing Lama,Divya Catherine Thomas,Pushkar Sharma,Shruti Agarwal,Selina Kern,Gabriele Pradel,Michele Graciotti,Andrew B. Tobin,Christian Doerig,Christian Doerig,Christian Doerig +32 more
TL;DR: This work identifies 1177 phosphorylation sites on 650 parasite proteins that are involved in a wide range of general cellular activities such as DNA synthesis, transcription and metabolism as well as key parasite processes such as invasion and cyto-adherence and defines potential anti-malarial drug targets within the parasite kinome.
Journal Article
ATP-site directed inhibitors of cyclin-dependent kinases.
TL;DR: Knowing the CDK/inhibitor interactions will be of great help to design inhibitors with improved selectivity and potency as well as to generate affinity chromatography matrices for the purification and identification of their cellular targets.