C
Christian Meisel
Researcher at Charité
Publications - 204
Citations - 9983
Christian Meisel is an academic researcher from Charité. The author has contributed to research in topics: Medicine & Stroke. The author has an hindex of 44, co-authored 181 publications receiving 7322 citations. Previous affiliations of Christian Meisel include Dresden University of Technology & Boston Children's Hospital.
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Journal ArticleDOI
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.
Jonas Schulte-Schrepping,Nico Reusch,Daniela Paclik,Kevin Baßler,Stephan Schlickeiser,Bowen Zhang,Benjamin Krämer,Tobias Krammer,Sophia Brumhard,Lorenzo Bonaguro,Elena De Domenico,Daniel Wendisch,Martin Grasshoff,Theodore S. Kapellos,Michael Beckstette,Tal Pecht,Adem Saglam,Oliver Dietrich,Henrik E. Mei,Axel Schulz,Claudia Conrad,Désirée Kunkel,Ehsan Vafadarnejad,Cheng-Jian Xu,Cheng-Jian Xu,Arik Horne,Miriam Herbert,Anna Drews,Charlotte Thibeault,Moritz Pfeiffer,Stefan Hippenstiel,Andreas C. Hocke,Holger Müller-Redetzky,Katrin-Moira Heim,Felix Machleidt,Alexander Uhrig,Laure Bosquillon de Jarcy,Linda Jürgens,Miriam Stegemann,Christoph R. Glösenkamp,Hans-Dieter Volk,Christine Goffinet,Markus Landthaler,Emanuel Wyler,Philipp Georg,Maria Schneider,Chantip Dang-Heine,Nick Neuwinger,Kai Kappert,Rudolf Tauber,Victor M. Corman,Jan Raabe,Kim Melanie Kaiser,Michael To Vinh,Gereon Rieke,Christian Meisel,Thomas Ulas,Matthias Becker,Robert Geffers,Martin Witzenrath,Christian Drosten,Norbert Suttorp,Christof von Kalle,Florian Kurth,Florian Kurth,Florian Kurth,Kristian Händler,Joachim L. Schultze,Joachim L. Schultze,Anna C. Aschenbrenner,Anna C. Aschenbrenner,Yang Li,Yang Li,Jacob Nattermann,Birgit Sawitzki,Antoine-Emmanuel Saliba,Leif E. Sander,Angel Angelov,Robert Bals,Alexander Bartholomäus,Anke Becker,Daniela Bezdan,Ezio Bonifacio,Peer Bork,Thomas Clavel,Maria Colomé-Tatché,Andreas Diefenbach,Alexander T. Dilthey,Nicole Fischer,Konrad U. Förstner,Julia-Stefanie Frick,Julien Gagneur,Alexander Goesmann,Torsten Hain,Michael Hummel,Stefan Janssen,Jörn Kalinowski,René Kallies,Birte Kehr,Andreas Keller,Sarah Kim-Hellmuth,Christoph Klein,Oliver Kohlbacher,Jan O. Korbel,Ingo Kurth,Kerstin U. Ludwig,Oliwia Makarewicz,Manja Marz,Alice C. McHardy,Christian Mertes,Markus M. Nöthen,Peter Nürnberg,Uwe Ohler,Stephan Ossowski,Jörg Overmann,Silke Peter,Klaus Pfeffer,Anna R. Poetsch,Alfred Pühler,Nikolaus Rajewsky,Markus Ralser,Olaf Rieß,Stephan Ripke,Ulisses Nunes da Rocha,Philip Rosenstiel,Philipp H. Schiffer,Eva-Christina Schulte,Alexander Sczyrba,Oliver Stegle,Jens Stoye,Fabian J. Theis,Janne Vehreschild,Jörg Vogel,Max von Kleist,Andreas Walker,Jörn Walter,Dagmar Wieczorek,John Ziebuhr +137 more
TL;DR: This study provides detailed insights into the systemic immune response to SARS-CoV-2 infection and it reveals profound alterations in the myeloid cell compartment associated with severe COVID-19.
Journal ArticleDOI
Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial.
Christian Meisel,Joerg C. Schefold,Rene Pschowski,Tycho Baumann,Katrin Hetzger,Jan Gregor,Steffen Weber-Carstens,Dietrich Hasper,Didier Keh,H. Zuckermann,Petra Reinke,Hans-Dieter Volk +11 more
TL;DR: Biomarker-guided GM-CSF therapy in sepsis is safe and effective for restoring monocytic immunocompetence and may shorten the time of mechanical ventilation and hospital/intensive care unit stay.
Journal ArticleDOI
Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses.
Anthony J. Coyle,Clare M. Lloyd,Jane Tian,Trang Nguyen,Christina Erikkson,Lin Wang,Par Ottoson,Per Persson,Tracy Delaney,Sophie M. Lehar,Steve Lin,Louis Poisson,Christian Meisel,Thomas Kamradt,Torbjörn Bjerke,Douglas Adam Levinson,Jose-Carlos Gutierrez-Ramos +16 more
TL;DR: It is suggested that T1/ST2 may prove to be a novel target for the selective suppression of Th2 immune responses in Th1- and Th2-mediated lung mucosal immune responses.
Journal ArticleDOI
Stroke-Induced Immunodepression Experimental Evidence and Clinical Relevance
Ulrich Dirnagl,Juliane Klehmet,Johann S. Braun,Hendrik J. Harms,Christian Meisel,Tjalf Ziemssen,Konstantin Prass,Andreas Meisel +7 more
TL;DR: Clinical evidence is emerging demonstrating that stroke-induced immunodepression in humans not only exists, but has very similar features to those characterized in rodent experiments.
Journal ArticleDOI
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity.
Marcin F. Osuchowski,Martin Sebastian Winkler,Tomasz Skirecki,Sara Cajander,Manu Shankar-Hari,Manu Shankar-Hari,Gunnar Lachmann,Guillaume Monneret,Fabienne Venet,Michael Bauer,Frank M. Brunkhorst,Sebastian Weis,Alberto García-Salido,Matthijs Kox,Jean-Marc Cavaillon,Florian Uhle,Markus A. Weigand,Stefanie B. Flohé,W. Joost Wiersinga,Raquel Almansa,Amanda de la Fuente,Ignacio Martin-Loeches,Christian Meisel,Thibaud Spinetti,Joerg C. Schefold,Catia Cilloniz,Antoni Torres,Antoni Torres,Evangelos J. Giamarellos-Bourboulis,Ricard Ferrer,Ricard Ferrer,Massimo Girardis,Andrea Cossarizza,Mihai G. Netea,Mihai G. Netea,Mihai G. Netea,Tom van der Poll,Jesus F. Bermejo-Martin,Ignacio Rubio +38 more
TL;DR: The authors reviewed the intricacies of COVID-19 pathophysiology, its various phenotypes, and the anti-SARS-CoV-2 host response at the humoral and cellular levels.