Author
Christian V. Stevens
Other affiliations: Katholieke Universiteit Leuven, University of Minnesota, VU University Amsterdam
Bio: Christian V. Stevens is an academic researcher from Ghent University. The author has contributed to research in topics: Ionic liquid & Bicyclic molecule. The author has an hindex of 45, co-authored 467 publications receiving 11742 citations. Previous affiliations of Christian V. Stevens include Katholieke Universiteit Leuven & University of Minnesota.
Papers published on a yearly basis
Papers
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TL;DR: In this article, 1,1-Bisphosphono-2-aza-1,3-dienes are formed by 1,4-dehydrohalogenation of the corresponding N-(bisphosphonomethyl)-α-haloimines in moderate to good yields.
Abstract: 1,1-Bisphosphono-2-aza-1,3-dienes are formed by 1,4-dehydrohalogenation of the corresponding N-(bisphosphonomethyl)-α-haloimines in moderate to good yields. The precursors could be formed by condensation of bisphosphono-amines and the corresponding α-haloaldehydes.
TL;DR: In this paper, a straightforward synthesis of new cis-4-aryl-3-chloro-2-azetidinones was developed, using a halogen-lithium exchange reaction on 4-aryl 3,3-dichloro-1,2-hexadecane.
Abstract: A straightforward synthesis of new cis-4-aryl-3-chloro-2-azetidinones was developed, using a halogen-lithium exchange reaction on 4-aryl-3,3-dichloro-2-azetidinones. This methodology was further extended to the use of alkyl halides as electrophiles, while more complex electrophiles could not be introduced.
01 Jan 2014
TL;DR: An overview of the existing entries to alkenes, geminally substituted with both a halogen and a heteroatom other than a chalcogen, can be found in this article.
Abstract: An overview is presented of the hitherto reported entries to alkenes, geminally substituted with both a halogen and a heteroatom other than a halogen or a chalcogen. The covered methodologies have been categorized according to the chemical class of the precursor molecule and the nature of the transformation yielding the gem-difunctionalized alkene. This work discusses primary literature reports up to the end of 2012.
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TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality.
Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …
33,785 citations
Journal Article•
28,685 citations
28 Jul 2005
TL;DR: PfPMP1）与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作�ly.
Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。
18,940 citations
TL;DR: In this paper, a review of cost effective technologies and the processes to convert biomass into useful liquid bio-fuels and bioproducts, with particular focus on some biorefinery concepts based on different feedstocks aiming at the integral utilization of these feedstocks for the production of value added chemicals.
Abstract: Sustainable economic and industrial growth requires safe, sustainable resources of energy. For the future re-arrangement of a sustainable economy to biological raw materials, completely new approaches in research and development, production, and economy are necessary. The ‘first-generation’ biofuels appear unsustainable because of the potential stress that their production places on food commodities. For organic chemicals and materials these needs to follow a biorefinery model under environmentally sustainable conditions. Where these operate at present, their product range is largely limited to simple materials (i.e. cellulose, ethanol, and biofuels). Second generation biorefineries need to build on the need for sustainable chemical products through modern and proven green chemical technologies such as bioprocessing including pyrolysis, Fisher Tropsch, and other catalytic processes in order to make more complex molecules and materials on which a future sustainable society will be based. This review focus on cost effective technologies and the processes to convert biomass into useful liquid biofuels and bioproducts, with particular focus on some biorefinery concepts based on different feedstocks aiming at the integral utilization of these feedstocks for the production of value added chemicals.
2,814 citations
TL;DR: Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. S. Nagar, Punjab-160 062, India, Institute of Biochemistry, Faculty of Medicine, Polytechnic University, Via Ranieri 67, IT-60100 Ancona, Italy, and Department of Medicinal Chemistry & Natural Products,The Hebrew University of Jerusalem, School of Pharmacy-Faculty of medicine, Jerusalem 91120, Israel.
Abstract: Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. A. S. Nagar,Mohali, Punjab-160 062, India, Institute of Biochemistry, Faculty of Medicine, Polytechnic University, Via Ranieri 67, IT-60100 Ancona, Italy,Green Biotechnology Research Group, The Special Division for Human Life Technology, National Institute of Advanced Industrial Science andTechnology, 1-8-31 Midorigaoka, Ikeda, Osaka-563-8577, Japan, and Department of Medicinal Chemistry & Natural Products,The Hebrew University of Jerusalem, School of Pharmacy-Faculty of Medicine, Jerusalem 91120, IsraelReceived March 2, 2004
2,570 citations