Christina Mauritz

TL;DR: The aim of this study was to characterize the cardiac differentiation potential of a murine iPS cell clone in comparison to a well-established murine ES cell line, and found that iPS cells differentiate into functional cardiomyocytes.

TL;DR: A first proof of concept study evaluates the potential of a murine iPSC-derived cardiovascular progenitor population, which expresses the surface marker foetal liver kinase-1 (Flk-1), to restore myocardial tissue and improve cardiac function after acuteMyocardial infarction (MI) in mice and paves the way for an autologous i PSC-based therapy of MI.

TL;DR: A fast protocol that can be used to obtain highly purified cultures of proliferating adult human and rat Schwann cells accessible for non-viral transfection methods and results in Schwann cell cultures that are more than 90–95% pure.

TL;DR: A fast protocol is presented that could be used to obtain highly purified cultures of maximal proliferating adult rat Schwann cells, which can be transfected in a nonbiological way using the physical transfection method of electroporation.

TL;DR: The results demonstrate the differentiation of AT2-like cells from mESCs after serum-induction and under serum-free conditions and will facilitate the identification of key differentiation factors leading to a more specific and effective generation of AT1- like cells from ESCs.