C
Christine M. Hunt
Researcher at Duke University
Publications - 80
Citations - 4249
Christine M. Hunt is an academic researcher from Duke University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 27, co-authored 69 publications receiving 3889 citations. Previous affiliations of Christine M. Hunt include Durham University & VCU Medical Center.
Papers
More filters
Journal ArticleDOI
Case definition and phenotype standardization in drug-induced liver injury
Guruprasad P. Aithal,Paul B. Watkins,Raúl J. Andrade,Dominique Larrey,Mariam Molokhia,Hajime Takikawa,Christine M. Hunt,Russell A. Wilke,Mark I. Avigan,Neil Kaplowitz,Einar Björnsson,Ann K. Daly +11 more
TL;DR: An international DILI Expert Working Group of clinicians and scientists reviewed current DILi terminology and diagnostic criteria so as to develop more uniform criteria that would define and characterize the spectrum of clinical syndromes that constitute D ILI.
Journal ArticleDOI
Prevalence and Clinical Correlates of YMDD Variants during Lamivudine Therapy for Patients with Chronic Hepatitis B
Ching-Lung Lai,Jules L. Dienstag,Eugene R. Schiff,Nancy Leung,Mark Atkins,Christine M. Hunt,Nathaniel A. Brown,Mary Woessner,Richard Boehme,Lynn D. Condreay +9 more
TL;DR: Patients with YMDD variants losing clinical response with a significant increase in the HBV DNA and ALT levels may require additional therapy.
Journal ArticleDOI
Effect of age and gender on the activity of human hepatic CYP3A
TL;DR: CYP3A activity was unaffected by age over the range of 27-83 years, suggesting that the aging-related alteration in the clearance of CYP3A substrates is secondary to changes in liver blood flow, size, or drug binding and distribution with aging.
Journal ArticleDOI
Clinical relevance of hepatitis B viral mutations.
Journal ArticleDOI
Iron reduction as an adjuvant to interferon therapy in patients with chronic hepatitis C who have previously not responded to interferon: A multicenter, prospective, randomized, controlled trial
Adrian M. Di Bisceglie,Herbert L. Bonkovsky,Sanjiv Chopra,S.L. Flamm,Rajender Reddy,Norman D. Grace,Paul G. Killenberg,Christine M. Hunt,Carlo H. Tamburro,Anthony S. Tavill,Roy Ferguson,Edward L. Krawitt,Barbara F. Banner,Bruce R. Bacon +13 more
TL;DR: Although prior phlebotomy therapy does not improve the rate of sustained response to interferon retreatment, it does result in less liver injury manifested by a decrease in serum transaminase activity and a slight improvement in liver histopathology.