C
Christoph Gohlke
Researcher at University of California, Irvine
Publications - 9
Citations - 12690
Christoph Gohlke is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Quenching (fluorescence) & Array programming. The author has an hindex of 8, co-authored 9 publications receiving 3481 citations. Previous affiliations of Christoph Gohlke include Max Planck Society & University of Illinois at Urbana–Champaign.
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Journal ArticleDOI
Array programming with NumPy
Charles R. Harris,K. Jarrod Millman,Stefan van der Walt,Stefan van der Walt,Ralf Gommers,Pauli Virtanen,David Cournapeau,Eric Wieser,Julian Taylor,Sebastian Berg,Nathaniel J. Smith,Robert Kern,Matti Picus,Stephan Hoyer,Marten H. van Kerkwijk,Matthew Brett,Matthew Brett,Allan Haldane,Jaime Fernández del Río,Mark Wiebe,Mark Wiebe,Pearu Peterson,Pierre Gérard-Marchant,Kevin Sheppard,Tyler Reddy,Warren Weckesser,Hameer Abbasi,Christoph Gohlke,Travis E. Oliphant +28 more
TL;DR: In this paper, the authors review how a few fundamental array concepts lead to a simple and powerful programming paradigm for organizing, exploring and analysing scientific data, and their evolution into a flexible interoperability layer between increasingly specialized computational libraries is discussed.
Journal ArticleDOI
Array Programming with NumPy
Charles R. Harris,K. Jarrod Millman,Stefan van der Walt,Stefan van der Walt,Ralf Gommers,Pauli Virtanen,David Cournapeau,Eric Wieser,Julian Taylor,Sebastian Berg,Nathaniel J. Smith,Robert Kern,Matti Picus,Stephan Hoyer,Marten H. van Kerkwijk,Matthew Brett,Matthew Brett,Allan Haldane,Jaime Fernández del Río,Mark Wiebe,Mark Wiebe,Pearu Peterson,Pierre Gérard-Marchant,Kevin Sheppard,Tyler Reddy,Warren Weckesser,Hameer Abbasi,Christoph Gohlke,Travis E. Oliphant +28 more
TL;DR: How a few fundamental array concepts lead to a simple and powerful programming paradigm for organizing, exploring and analysing scientific data is reviewed.
Journal ArticleDOI
A three-dimensional model for the hammerhead ribozyme based on fluorescence measurements
TL;DR: FRET was used to study the structure of the ribozyme in solution in order to establish the relative spatial orientation of the three constituent Watson-Crick base-paired helical segments and the FRET efficiencies were predicted on the basis of vector algebra analysis and compared with experimental values.
Journal ArticleDOI
Kinking of DNA and RNA helices by bulged nucleotides observed by fluorescence resonance energy transfer
TL;DR: The FRET efficiency for DNA molecules with A9 bulges is lower than the efficiency for the corresponding A7 bulged molecules, although the A9 molecules exhibit increased electrophoretic retardation.
Journal ArticleDOI
Fluorescence characteristics of 5-carboxytetramethylrhodamine linked covalently to the 5' end of oligonucleotides: Multiple conformers of single-stranded and double-stranded dye-DNA complexes
TL;DR: Fluorescence steady-state and lifetime experiments have been carried out on duplex and single-stranded DNA molecules labeled at the 5' ends with 5-carboxytetramethylrhodamine (TMRh), revealing at least three well-defined states of the TMRh-DNA molecules for the single-Stranded as well as for the double-stranding DNA molecules.