Christoph Scholtissek

TL;DR: It is shown that these H5N1 viruses are reverting to nonpathogenicity in ducks, suggesting that the duck has become the "Trojan horse" of Asian H 5N1 influenza viruses.

TL;DR: The high homology between the internal genes of H9N2, H6N1, and the H5N1 isolates indicates that these subtypes are able to exchange their internal genes and are therefore a potential source of new pathogenic influenza virus strains.

TL;DR: In the A/Wuhan/359/95 (H3N2) recombinant virus background, seven charged, conserved NA residues were characterized that directly interact with the NAIs but have not been reported to confer resistance to NAIs.

TL;DR: Although the authors failed to identify compounds that interacted with the ion channel of amantadine-resistant variants and inhibited their replication, they were able to construct at least two compounds that interfered with both the ions channel and the hemagglutinin at about the same concentration.

TL;DR: The mutation rates of A/Mallard/New York/6750/78 (H2N2) and A/Swine/Germany/2/81 (H1N1) were calculated by using the frequency of amantadine-resistant mutants and a probabilistic model for the statistical analysis found the resulting estimated mutation rates were not significantly different.