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Christophe Wiart

Bio: Christophe Wiart is an academic researcher from University of Nottingham Malaysia Campus. The author has contributed to research in topics: Medicine & Acanthamoeba. The author has an hindex of 21, co-authored 108 publications receiving 2056 citations. Previous affiliations of Christophe Wiart include Universiti Putra Malaysia & University of Nottingham.
Topics: Medicine, Acanthamoeba, DPPH, Biology, Phytochemical


Papers
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Journal ArticleDOI
TL;DR: The results demonstrated that the assays displayed a high (R ≥ 0.82) and significant (P < 0.0001) correlation with one another, indicating a high level of redundancy if all three assays are used in parallel, which appears to be a waste of potentially valuable plant extracts.
Abstract: Extracts of plants from the Malaysian rainforest and other fragile habitats are being researched intensively for identification of beneficial biological actions, with assessment of antioxidant behavior being a common component of such assessments. A number of tests for antioxidant behavior are used, with the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reduction activity potential (FRAP) assays often being used in parallel, and also with measurement of total phenolics content (TPC) as a surrogate marker for antioxidant capacity. The present study investigated the possible redundancy in using all three assays to determine antioxidant capacity in 92 extracts obtained from 27 plants from the Malaysian rainforest. The results demonstrated that the assays displayed a high (R ≥ 0.82) and significant (P < 0.0001) correlation with one another, indicating a high level of redundancy if all three assays are used in parallel. This appears to be a waste of potentially valuable plant extracts. Because of problems with the FRAP assay relating to color interference and variable rates of reaction point, the DPPH assay is the preferred assay in preliminary screening of extracts of plants from the Malaysian rainforest.

226 citations

Journal ArticleDOI
TL;DR: None of the compounds isolated from Andrographis paniculata exhibited significant cytotoxicity at viricidal concentrations.
Abstract: Andrographolide, neoandrographolide and 14-deoxy-11,12-didehydroandrographolide, ent-labdene diterpenes isolated from Andrographis paniculata showed viricidal activity against herpes simplex virus 1 (HSV-1). None of these compounds exhibited significant cytotoxicity at viricidal concentrations.

191 citations

Journal ArticleDOI
TL;DR: In this article, the authors used the leaves, barks, and roots of 50 plant species used in the traditional medicine of Perak, Peninsular Malaysia, have been screened for antibacterial and antifungal activities.

171 citations

Book
19 Jun 2006
TL;DR: This chapter discusses medicinal Plants in the Family Annonaceae, focusing on the phytochemical properties of Fissistima lanuginosum, which is a synthesis of the fruit of fissistigma manubriatum and phytochemistry.
Abstract: Introduction Medicinal Plants Classified in the Family Annonaceae General Concept Fissistima lanuginosum (Hk f et Th) Merr Fissistigma manubriatum (Hk f et Th) Phaeanthus ebracteolatus (Prels) Merr References Medicinal Plants Classified in the Family Myristicaceae General Concept Knema glaucescens Jack Knema Globularia (Lamk) Warb Myristica argentea Warb Myristica elliptica Wall Ex Hook F Thoms References Medicinal Plants Classified in the Family Lauraceae General Concept Cinnamomun sintoc Bl Beilschmiedia pahangensis Gamb Bielschmiedia tonkinensis Ridl Cryptocarya griffithiana Wight Cryptocarya tomentosa Bl Litsea umbellata (Lour) Merr References Medicinal Plants Classified in the Family Piperaceae General Concept Piper Abbreviatum Opi Piper betle L Piper officinarum DC Piper sarmentosum Roxb References Medicinal Plants Classified in the Family Aristolochiaceae General Concept Aristolochia philippinensis Warb References Medicinal Plants Classified in the Family Nympheaceae General Concept Nelumbo nucifera Gaertn Nymphea Pubescens Willd Nymphea stellata Willd References Medicinal Plants Classified in the Family Menispermaceae General Concept Arcangelica flava (L) Merr Limacia oblonga Hook f & Thoms Stephania Japonica (Thunb) Miers References Medicinal Plants Classified in the Family Polygonaceae General Concept Polygonum chinense L Polygonum Minus Huds Polygonum tomentosum Willd References Medicinal Plants Classified in the Family Myrsinaceae General Concept Aegiceras corniculatum Blco Aridisia corolata Roxb Ardisia elliptica Thunb Ardisia fuliginosa Bl Ardisia humilis Vahl Ardisia lanceolata Roxb Ardisia odontophylla Wall Ardisia oxyphylla Wall Ardisia pyramidalis (Cav) Pers Ardisia ridleyi King & Gamble Ardisia squamulosa Presl Maesa cumingii Mez Maesa denticullata Mez Maesa laxa Mez Maesa perlarius (Lour) Merr Maesa ramentacea (Roxb) ADC Maesa tetrandra A DC References Medicinal Plants Classified in the Family Ebenaceae General Concept Diospyros lanceifolia Roxb Diospyros malabarica (Desr) Kostel Diospyros multiflora Blco Diospyros pilosanthera Blco Diospyros sumatrana Miq Diospyros rufa King & Gamble Diospyros toposioides King & Gamble References Medicinal Plants Classified in the Family Bombacaceae General Concept Ceiba pentandra (L) Gaertn Neesia Altissima Bl References Medicinal Plants Classified in the Family Elaeocarpaceae General Concept Elaeocarpus floribundus Bl Elaeocarpus obtusus Bl sensu King References Medicinal Plants Classified in the Family Capparaceae General Concept Capparis micrantha DC Crateva religiosa Forts References Medicinal Plants Classified in the Family Flacourtiaceae General Concept Flacourtia jangomas (Lour) Raeusch Homalium tomentosum (Vent) Benth Hydnocarpus kurzii ssp Australis Sleumer References Medicinal Plants Classified in the Family Passifloraceae General Concept Adenia cordifolia Engl Passiflora foetida L Passiflora quadrangularis L Passiflora laurifolia L References Medicinal Plants Classified in the Family Cucurbitaceae General Concept Gymnopetalum cochinchinense (Lour) Kurz Hodgsonia macrocarpa (Bl) Cogn Trichosanthes quinquangulata A Grey Trichosanthes tricuspidata Lour Trichosanthes villosa Bl Trichosanthes wawrae Cogn References Medicinal Plants Classified in the Family Connaraceae General Concept Connarus ferrugineus Jack References Medicinal Plants Classified in the Family Anisophylleaceae General Concept Anisophyllea disticha Hook f Reference Medicinal Plants Classified in the Family Rosaceae General Concept Eriobotrya japonica (Thunb) Lindl Prunus arborea (Bl) Kalkman Rubus moluccanum L References Medicinal Plants Classified in the Family Thymeleaceae General Concept Gonystylus confusus Airy Shaw Gonystylus macrophyllus (Miq) Airy Shaw References Medicinal Plants Classified in the Family Melastomataceae General Concept Blastus cogniauxii Stapf Diplectra divaricata (Willd) O Ktze Dissochaeta annulata Hook f Dissochaeta bracteata (Jack) Bl Dissochaeta punctulata Hook f ex Triana Medinilla hasseltiI Bl Medinilla radicans (Bl) Bl Melastoma polyanthum Bl Melasatoma sanguineum Sims Memecylon dichotomum CB Clarke Neodissochaeta gracilis (Jack) Bakh f Osbeckia chinensis L Pternandra coerulescens Jack References Medicinal Plants Classified in the Family Rhizophoraceae General Concept Bruguiera sexangula (Lour) Poir Carallia brachiata (Lour) Merr Carallia suffruticosa King Ceriops tagal (Pers) CB Rob Gynotroches axillaris Bl Rhizophora apiculata Bl Rhizophora mucronata Lamk References Medicinal Plants Classified in the Family Olacaceae General Concept Ochanostachys amentacea Mast Ximenia americana L Strombosia philippinensis (Baill) Rolfe References Medicinal Plants Classified in the Family Icacinaceae General Concept Gonocaryum gracile Miq References Medicinal Plants Classified in the Family Euphorbiaceae General Concept Antidesma ghaemsembilla Gaertn Euphorbia thymifolia L Macaranga tanarius Muell-Arg References Medicinal Plants Classified in the Family Sapindaceae General Concept Dodonaea viscosa (L) Jacq Lepisanthes tetraphylla (Vahl) Radlk Nephelium juglandifolium Bl Pometia pinnata Forst References Medicinal Plants Classified in the Family Anacardiaceae General Concept Dracontomelon dao (Blanco) Merr & Rolfe Gluta rhengas L Melanochyla auriculata Hook f Pentaspadon officinalis Holmes References Medicinal Plants Classified in the Family Simaroubaceae General Concept Eurycoma apiculata Benn Quassia indica (Gaertn) Nootebom References Medicinal Plants Classified in the Family Meliaceae General Concept Aglaia odorata Lour Aphanamixis grandifolia Bl Aphanamixis rohituka (Roxb) Pierre Chisocheton penduliflorus Planch ex Hiern Dysoxylum alliaceum Bl Dysoxylum cauliflorum Hiern Sandoricum koejape (Burm f) Merr Toona sureni (Bl) Merr Trichilia connaroide (Wight & Arn) Bentvelzen Xylocarpus granatum Koenig Xylocarpus moluccensis (Lamk) Roem References Medicinal Plants Classified in the Family Rutaceae General Concept Aegle marmelos Correa Atalantia monophylla DC Atalantia roxburghiana Hook f Citrus hystrix DC Citrus mitis Blco Clausena excavata Burm f Clausena lansium (Lour) Skeells Euodia elleryana F Muell Lunasia amara Blco Micromelum minutum (Forst f) W & A Paramignya andamanica Tanaka Toddalia asiatica (L) Lamk Zanthoxylum avicennae (Lamk) DC Zanthoxylum myriacanthum Wall ex Hk f References Medicinal Plants Classified in the Family Loganiaceae General Concept Fagraea auriculata Jack Fagraea blumei GDon Fagraea obovata (non Wall) King Neuburgia corynocarpa (A Gray) Leenh References Medicinal Plants Classified in the Family Gentianaceae General Concept Nymphoides indica (Thwaites) Kuntze Swertia javanica Bl References Medicinal Plants Classified in the Family Apocynaceae General Concept Alstonia angustifolia Wall ex A Dc Alstonia macrophylla Wall ex G Don Alstonia spectabilis Alstonia spatulata Bl Carissa carandas L Epigynum maingayi Hook f Ervatamia sphaerocarpa Bl Holarrhena curtisii King & Gamble Kibatalia arborea (Bl) GDon Kopsia larutensis King & Gamble Willughbeia edulis Ridl Wrightia pubescens R Br References Medicinal Plants Classified in the Family Asclepiadaceae General Concept Hoya coriacea Bl Hoya coronaria Bl Hoya diversifolia Bl Streptocaulon cumingii (Turcz) F-Vill Telosma cordata (Burmf) Merr References Medicinal Plants Classified in the Family Solanaceae General Concept Capsicum minimum Roxb Solanum ferox var laniocarpum Solanum mammosum L Solanum nigrum L Solanum verbascifolium L References Medicinal Plants Classified in the Family Verbenaceae General Concept Callicarpa arborea Roxb Clerodendrum dDeflexum Wall Clerodendrum inerm (L) Gaertn Duranta plumieri Jacq Gmelina elliptica Sm Peronema canescens Jack Sphenodesme pentandra Jack Sphenodesme trifolia Wight Teijmanniodendron pteropodium (Miq) Bakh References Index

158 citations


Cited by
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Journal ArticleDOI
TL;DR: The past, present and future of medicinal plants are analyzed, both as potential antimicrobial crude drugs as well as a source for natural compounds that act as new anti-infection agents.

1,665 citations

Journal ArticleDOI
TL;DR: The knowledge of the development of ideas related to the usage of medicinal plants as well as the evolution of awareness has increased the ability of pharmacists and physicians to respond to the challenges that have emerged with the spreading of professional services in facilitation of man's life.
Abstract: Healing with medicinal plants is as old as mankind itself. The connection between man and his search for drugs in nature dates from the far past, of which there is ample evidence from various sources: written documents, preserved monuments, and even original plant medicines. Awareness of medicinal plants usage is a result of the many years of struggles against illnesses due to which man learned to pursue drugs in barks, seeds, fruit bodies, and other parts of the plants. Contemporary science has acknowledged their active action, and it has included in modern pharmacotherapy a range of drugs of plant origin, known by ancient civilizations and used throughout the millennia. The knowledge of the development of ideas related to the usage of medicinal plants as well as the evolution of awareness has increased the ability of pharmacists and physicians to respond to the challenges that have emerged with the spreading of professional services in facilitation of man's life.

881 citations

Journal ArticleDOI
01 May 1949-Nature
TL;DR: The Wealth of India: A Dictionary of Indian Raw Materials and Industrial Products as mentioned in this paper is a dictionary of the economic products of India that was published during the years 1889-99 by the Government of India.
Abstract: IT may occasion some surprise to those men of science who are ill-acquainted with India, and who so frequently express the view that Governments are unappreciative of the importance of science to learn that as far back as 1886 the Government of India arranged for Dr. George (later Sir George) Watt, professor of botany in the Presidency College, Calcutta, to prepare a "Dictionary of the Economic Products of India". The six volumes of this standard work were published during the years 1889-99. In 1908 Sir George Watt published a condensed version, "The Commercial Products of India". Whatever the defects of these 'dictionaries', they have been of inestimable value to all interested in Indian natural products. The Wealth of India A Dictionary of Indian Raw Materials and Industrial Products. Raw Materials, Vol. 1. Pp. xxvii+254+39 plates. 15 rupees ; 24s. Industrial Products, Part 1. Pp. xii+182+8 plates. 8 rupees ; 12s. (New Delhi : Council of Scientific and Industrial Research, 1948.)

694 citations

Journal ArticleDOI
01 Dec 2008

636 citations

Journal ArticleDOI
TL;DR: This review covers the literature on simple indole alkaloid and those with a nonrearranged monoterpenoid unit from the beginning of 2012 up to the end of 2013, which includes newly isolated alkaloids, structure determinations, total syntheses and biological activities.

463 citations